TGFA
Protransforming growth factor alpha
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
PubMedID | 0.95 | ||
biological term | 0.92 | ||
chemical | 0.84 | ||
biological process | 0.82 | ||
disease | 0.82 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Asparagine N-linked glycosylation | ||||
Reactome | COPII-mediated vesicle transport | ||||
Reactome | Cargo concentration in the ER | ||||
Reactome | Cargo recognition for clathrin-mediated endocytosis | ||||
Reactome | Clathrin-mediated endocytosis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Asparagine N-linked glycosylation | ||||
COPII-mediated vesicle transport | ||||
Cargo concentration in the ER | ||||
Cargo recognition for clathrin-mediated endocytosis | ||||
Clathrin-mediated endocytosis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | HGNC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
grip strength measurement | 4 | 3 | 4 | 78.4 | |||||
3 | 3 | 0 | 1.1 | 77.1 | |||||
heel bone mineral density | 2 | 2 | 2 | 69.1 | |||||
1 | 1 | 0 | 1.1 | 66 | |||||
1 | 1 | 0 | 1.1 | 57.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
grip strength measurement | 4 | 78.4 | |||||
0 | 1.1 | 77.1 | |||||
heel bone mineral density | 2 | 69.1 | |||||
0 | 1.1 | 66 | |||||
0 | 1.1 | 57.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | transforming growth factor alpha | VGNC:479 | 737080 | |||||
Macaque | transforming growth factor alpha | 613031 | ||||||
Mouse | MGI:98724 | 21802 | ||||||
Rat | RGD:3849 | 24827 | ||||||
Horse | transforming growth factor alpha | VGNC:51415 | 100060423 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | transforming growth factor alpha | |||||
Macaque | transforming growth factor alpha | |||||
Mouse | ||||||
Rat | ||||||
Horse | transforming growth factor alpha | |||||
PMID | Year | Title |
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