OAS1
2'-5'-oligoadenylate synthase 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 1 | ||
virus perturbation | 1 | ||
PubMedID | 0.98 | ||
molecular function | 0.96 | ||
kinase perturbation | 0.91 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Antiviral mechanism by IFN-stimulated genes | ||||
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Immune System | ||||
Reactome | Interferon Signaling | ||||
Reactome | Interferon alpha/beta signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Antiviral mechanism by IFN-stimulated genes | ||||
Cytokine Signaling in Immune system | ||||
Immune System | ||||
Interferon Signaling | ||||
Interferon alpha/beta signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 1 | 1 | 1 | 83.2 | |||||
alcohol drinking | 1 | 1 | 0 | 1.6 | 66.3 | ||||
alcohol consumption measurement | 1 | 1 | 0 | 1.6 | 66.3 | ||||
high density lipoprotein cholesterol measurement | 1 | 1 | 0 | 1.4 | 52.4 | ||||
COVID-19 | 1 | 1 | 0 | 1.2 | 35 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 1 | 83.2 | |||||
alcohol drinking | 0 | 1.6 | 66.3 | ||||
alcohol consumption measurement | 0 | 1.6 | 66.3 | ||||
high density lipoprotein cholesterol measurement | 0 | 1.4 | 52.4 | ||||
COVID-19 | 0 | 1.2 | 35 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | 2'-5'-oligoadenylate synthetase 1 | VGNC:5516 | 739129 | |||||
Macaque | 2'-5'-oligoadenylate synthetase 1 | 712265 | ||||||
Mouse | MGI:97429 | 23960 | ||||||
Rat | RGD:6497100 | 100910735 | ||||||
Dog | 2'-5'-oligoadenylate synthetase 1 | VGNC:44086 | 608778 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | 2'-5'-oligoadenylate synthetase 1 | |||||
Macaque | 2'-5'-oligoadenylate synthetase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | 2'-5'-oligoadenylate synthetase 1 | |||||
PMID | Year | Title |
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