PLAU
Urokinase-type plasminogen activator
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.99 | ||
protein domain | 0.99 | ||
drug | 0.97 | ||
virus perturbation | 0.97 | ||
small molecule perturbation | 0.89 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Dissolution of Fibrin Clot | ||||
Reactome | Hemostasis | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | Neutrophil degranulation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Dissolution of Fibrin Clot | ||||
Hemostasis | ||||
Immune System | ||||
Innate Immune System | ||||
Neutrophil degranulation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
urokinase plasminogen activator surface receptor measurement | 1 | 1 | 1 | 82.3 | |||||
forced expiratory volume | 1 | 2 | 2 | 76.4 | |||||
FEV/FEC ratio | 1 | 2 | 2 | 63.6 | |||||
1 | 1 | 0 | 1.1 | 61.4 | |||||
1 | 1 | 0 | 1.1 | 56.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
urokinase plasminogen activator surface receptor measurement | 1 | 82.3 | |||||
forced expiratory volume | 2 | 76.4 | |||||
FEV/FEC ratio | 2 | 63.6 | |||||
0 | 1.1 | 61.4 | |||||
0 | 1.1 | 56.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | plasminogen activator, urokinase | 738078 | ||||||
Macaque | plasminogen activator, urokinase | 705853 | ||||||
Mouse | MGI:97611 | 18792 | ||||||
Rat | RGD:3343 | 25619 | ||||||
Dog | plasminogen activator, urokinase | VGNC:52017 | 403426 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | plasminogen activator, urokinase | |||||
Macaque | plasminogen activator, urokinase | |||||
Mouse | ||||||
Rat | ||||||
Dog | plasminogen activator, urokinase | |||||
PMID | Year | Title |
---|