PNP
Purine nucleoside phosphorylase
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
kinase perturbation | 0.99 | ||
transcription factor perturbation | 0.96 | ||
biological process | 0.95 | ||
virus perturbation | 0.95 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of nucleotides | ||||
Reactome | Neutrophil degranulation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Immune System | ||||
Innate Immune System | ||||
Metabolism | ||||
Metabolism of nucleotides | ||||
Neutrophil degranulation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mitochondrial DNA measurement | 1 | 1 | 1 | 73.6 | |||||
metabolite measurement | 1 | 1 | 1 | 65.6 | |||||
aspartate aminotransferase measurement | 2 | 1 | 1 | 6.8 | 62.1 | ||||
1 | 1 | 0 | 1.6 | 27.3 | |||||
serum alanine aminotransferase measurement | 1 | 1 | 0 | 5.6 | 21.5 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mitochondrial DNA measurement | 1 | 73.6 | |||||
metabolite measurement | 1 | 65.6 | |||||
aspartate aminotransferase measurement | 1 | 6.8 | 62.1 | ||||
0 | 1.6 | 27.3 | |||||
serum alanine aminotransferase measurement | 0 | 5.6 | 21.5 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | purine nucleoside phosphorylase | VGNC:3356 | 737850 | |||||
Mouse | MGI:3712328 | 667034 | ||||||
Rat | RGD:1597189 | 290029 | ||||||
Dog | purine nucleoside phosphorylase | VGNC:44751 | 475393 | |||||
Horse | purine nucleoside phosphorylase-like | 100072592 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | purine nucleoside phosphorylase | |||||
Mouse | ||||||
Rat | ||||||
Dog | purine nucleoside phosphorylase | |||||
Horse | purine nucleoside phosphorylase-like | |||||
PMID | Year | Title |
---|