GLUD1
Glutamate dehydrogenase 1, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.99 | ||
disease perturbation | 0.97 | ||
hub protein | 0.97 | ||
interacting protein | 0.97 | ||
transcription factor binding site profile | 0.88 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Glutamate and glutamine metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of amino acids and derivatives | ||||
Reactome | Mitochondrial biogenesis | ||||
Reactome | Organelle biogenesis and maintenance | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Glutamate and glutamine metabolism | ||||
Metabolism | ||||
Metabolism of amino acids and derivatives | ||||
Mitochondrial biogenesis | ||||
Organelle biogenesis and maintenance | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Traceable Author Statement (TAS) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
urate measurement | 4 | 3 | 4 | 86.8 | |||||
5 | 4 | 0 | 1.4 | 86 | |||||
hemoglobin measurement | 2 | 2 | 2 | 75.7 | |||||
hematocrit | 2 | 2 | 2 | 66.6 | |||||
red blood cell density measurement | 1 | 1 | 1 | 63.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
urate measurement | 4 | 86.8 | |||||
0 | 1.4 | 86 | |||||
hemoglobin measurement | 2 | 75.7 | |||||
hematocrit | 2 | 66.6 | |||||
red blood cell density measurement | 1 | 63.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | glutamate dehydrogenase 1 | VGNC:3868 | 450576 | |||||
Macaque | glutamate dehydrogenase 1, mitochondrial | 693461 | ||||||
Mouse | MGI:95753 | 14661 | ||||||
Rat | RGD:2708 | 24399 | ||||||
Dog | glutamate dehydrogenase 1 | 100684847 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | glutamate dehydrogenase 1 | |||||
Macaque | glutamate dehydrogenase 1, mitochondrial | |||||
Mouse | ||||||
Rat | ||||||
Dog | glutamate dehydrogenase 1 | |||||
PMID | Year | Title |
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