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Tdark
OVOL3
Putative transcription factor ovo-like protein 3

Protein Summary
Description
May act as a transcription regulator.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000585332
  • ENSP00000465620
  • ENSG00000105261

Symbol
  • HOVO3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.61
transcription factor
0.49
cell line
0.45
biological process
0.41
protein complex
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.44   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.44   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
TMEM221
Tdark
Novelty:  6.39119451
Score:  0.621
Data Source:  STRINGDB
TMEM212
Tdark
Novelty:  0.94290731
Score:  0.594
Data Source:  STRINGDB
TMEM211
Tdark
Novelty:  6.51386952
Score:  0.581
Data Source:  STRINGDB
GPR137C
Tdark
Novelty:  3.30248948
Score:  0.574
Data Source:  STRINGDB
TMEM132E
Tdark
Novelty:  0.27039617
Score:  0.566
Data Source:  STRINGDB
TMEM171
Tdark
Novelty:  2.00247773
Score:  0.55
Data Source:  STRINGDB
TMEM150C
Tdark
Novelty:  0.11603552
Score:  0.543
Data Source:  STRINGDB
PRODH2
Tbio
Family:  Enzyme
Novelty:  0.09377289
Score:  0.54
Data Source:  STRINGDB
SNX32
Tdark
Novelty:  0.66136036
Score:  0.527
Data Source:  STRINGDB
GPR162
Tbio
Family:  GPCR
Novelty:  0.14938549
Score:  0.519
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (7)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
schizophrenia
1
1
0
1.1
33.1
appendicular lean mass
1
1
1
2.9
neutrophil percentage of leukocytes
1
1
1
1.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
schizophrenia
0
1.1
33.1
appendicular lean mass
1
2.9
neutrophil percentage of leukocytes
1
1.6
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ovo like zinc finger 3
VGNC:13302
748222
Mouse
MGI:2388075
381867
Dog
ovo like zinc finger 3
VGNC:44198
102153991
Horse
ovo like zinc finger 3
VGNC:51059
102148646
Opossum
ovo like zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:14186]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ovo like zinc finger 3
Mouse
Dog
ovo like zinc finger 3
Horse
ovo like zinc finger 3
Opossum
ovo like zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:14186]
Publication Statistics
PubMed Score 1.44
PubMed score by year
PubTator Score 1.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title