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Tbio
OVCA2
Esterase OVCA2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000572195
  • ENSP00000461388
  • ENSG00000262664
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.73
transcription factor binding site profile
0.66
tissue sample
0.6
tissue
0.46
virus perturbation
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.38   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 55   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.38   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 55   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
MYH11
Tbio
Novelty:  0.00142474
p_int:  0.999944126
p_ni:  0.000032861
p_wrong:  0.000023013
Score:  0.548
Data Source:  BioPlex,STRINGDB
PTPN11
Tchem
Family:  Enzyme
Novelty:  0.00073124
p_int:  0.907354017
p_ni:  0.092645982
Score:  0.241
Data Source:  BioPlex,STRINGDB
DPH1
Tbio
Novelty:  0.02296024
Score:  0.905
Data Source:  STRINGDB
SPATA6L
Tdark
Novelty:  3.37083829
Score:  0.838
Data Source:  STRINGDB
DPH2
Tbio
Novelty:  0.04268301
Score:  0.717
Data Source:  STRINGDB
DAZAP1
Tbio
Novelty:  0.04307077
Score:  0.637
Data Source:  STRINGDB
NXPH2
Tdark
Novelty:  0.65790631
Score:  0.548
Data Source:  STRINGDB
HSD17B12
Tbio
Family:  Enzyme
Novelty:  0.02200219
Score:  0.542
Data Source:  STRINGDB
SEPT9
Tchem
Novelty:  0.00407266
Score:  0.536
Data Source:  STRINGDB
HIC1
Tbio
Family:  TF
Novelty:  0.00734145
Score:  0.525
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Non-traceable Author Statement (NAS)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (37)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
4
7
97
2
2
1
1.1
87.1
platelet count
3
3
3
86
leukocyte count
3
3
3
85.4
neutrophil count
3
3
3
79
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
7
97
1
1.1
87.1
platelet count
3
86
leukocyte count
3
85.4
neutrophil count
3
79
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2179725
246257
Dog
OVCA2, serine hydrolase domain containing
VGNC:44195
611290
Horse
OVCA2, serine hydrolase domain containing
VGNC:21096
106780844
Cow
OVCA2, serine hydrolase domain containing
VGNC:32504
513845
Pig
OVCA2, serine hydrolase domain containing
106504187
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Dog
OVCA2, serine hydrolase domain containing
Horse
OVCA2, serine hydrolase domain containing
Cow
OVCA2, serine hydrolase domain containing
Pig
OVCA2, serine hydrolase domain containing
Publication Statistics
PubMed Score 9.38
PubMed score by year
PubTator Score 4.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title