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Tbio
OSGIN2
Oxidative stress-induced growth inhibitor 2

Protein Summary
Description
May be involved in meiosis or the maturation of germ cells.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297438
  • ENSP00000297438
  • ENSG00000164823
  • ENST00000451899
  • ENSP00000396445
  • ENST00000647849
  • ENSP00000497119

Symbol
  • C8orf1
  • hT41
  • C8orf1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.76
transcription factor binding site profile
0.76
virus perturbation
0.72
transcription factor
0.65
small molecule perturbation
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.17   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 113   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.17   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 113   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
CALB1
Tbio
Novelty:  0.00037716
Score:  0.837
Data Source:  STRINGDB
CA7
Tclin
Family:  Enzyme
Novelty:  0.00602131
Score:  0.716
Data Source:  STRINGDB
COA3
Tbio
Family:  Enzyme
Novelty:  0.04949473
Score:  0.714
Data Source:  STRINGDB
DECR1
Tbio
Family:  Enzyme
Novelty:  0.02699187
Score:  0.714
Data Source:  STRINGDB
GSTK1
Tchem
Family:  Enzyme
Novelty:  0.04205366
Score:  0.691
Data Source:  STRINGDB
SELENBP1
Tbio
Novelty:  0.00758018
Score:  0.683
Data Source:  STRINGDB
CALB2
Tbio
Novelty:  0.0004996
Score:  0.636
Data Source:  STRINGDB
MS4A7
Tdark
Novelty:  1.1093531
Score:  0.59
Data Source:  STRINGDB
LIN52
Tbio
Novelty:  0.08105335
Score:  0.506
Data Source:  STRINGDB
MSL1
Tbio
Novelty:  3.71231442
Score:  0.478
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
1
2
70.5
lymphocyte percentage of leukocytes
1
1
1
37.6
Oral ulcer
1
1
0
1.1
36.5
1
1
0
1.3
11.6
diastolic blood pressure
1
1
1
7.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
70.5
lymphocyte percentage of leukocytes
1
37.6
Oral ulcer
0
1.1
36.5
0
1.3
11.6
diastolic blood pressure
1
7.6
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
oxidative stress induced growth inhibitor family member 2
VGNC:828
472813
Macaque
oxidative stress induced growth inhibitor family member 2
695376
Mouse
MGI:2384798
209212
Rat
RGD:1306323
313085
Dog
oxidative stress induced growth inhibitor family member 2
VGNC:44165
487038
Species
Name
OMA
EggNOG
Inparanoid
Chimp
oxidative stress induced growth inhibitor family member 2
Macaque
oxidative stress induced growth inhibitor family member 2
Mouse
Rat
Dog
oxidative stress induced growth inhibitor family member 2
Publication Statistics
PubMed Score 5.17
PubMed score by year
PubTator Score 4.03
PubTator score by year
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Related Publications
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PMID
Year
Title