OSBPL6
Oxysterol-binding protein-related protein 6
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.97 | ||
trait | 0.86 | ||
histone modification site profile | 0.84 | ||
kinase perturbation | 0.81 | ||
transcription factor binding site profile | 0.75 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Bile acid and bile salt metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | Metabolism of steroids | ||||
Reactome | Synthesis of bile acids and bile salts | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Bile acid and bile salt metabolism | ||||
Metabolism | ||||
Metabolism of lipids | ||||
Metabolism of steroids | ||||
Synthesis of bile acids and bile salts | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
aspartate aminotransferase measurement | 1 | 1 | 0 | 8.1 | 65.6 | ||||
vital capacity | 1 | 1 | 1 | 47.7 | |||||
refractive error measurement | 1 | 1 | 1 | 38.2 | |||||
electrocardiography | 1 | 1 | 3 | 30.2 | |||||
forced expiratory volume | 1 | 1 | 1 | 30.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
aspartate aminotransferase measurement | 0 | 8.1 | 65.6 | ||||
vital capacity | 1 | 47.7 | |||||
refractive error measurement | 1 | 38.2 | |||||
electrocardiography | 3 | 30.2 | |||||
forced expiratory volume | 1 | 30.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | oxysterol binding protein like 6 | VGNC:2742 | 459775 | |||||
Macaque | oxysterol binding protein like 6 | 708349 | ||||||
Mouse | MGI:2139014 | 99031 | ||||||
Rat | RGD:1308887 | 311129 | ||||||
Dog | oxysterol binding protein like 6 | VGNC:44156 | 478816 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | oxysterol binding protein like 6 | |||||
Macaque | oxysterol binding protein like 6 | |||||
Mouse | ||||||
Rat | ||||||
Dog | oxysterol binding protein like 6 | |||||
PMID | Year | Title |
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