Protein Summary
Odorant receptor. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.09 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 96 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.09 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 96 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (37)
HMGCS1
Family: Enzyme
Novelty: 0.01089288
p_int: 0.988543713
p_ni: 0.011446564
p_wrong: 0.000009723
Score: 0.198
Data Source: BioPlex,STRINGDB
UBA6
Novelty: 0.05213412
p_int: 0.936211011
p_ni: 0.06378791
p_wrong: 0.000001079
Score: 0.234
Data Source: BioPlex,STRINGDB
FTO
Family: Enzyme
Novelty: 0.00053473
p_int: 0.918026942
p_ni: 0.081973058
Score: 0.189
Data Source: BioPlex,STRINGDB
CCDC25
Novelty: 0.22601722
p_int: 0.865352715
p_ni: 0.000302695
p_wrong: 0.13434459
Score: 0.403
Data Source: BioPlex,STRINGDB
IRGQ
Family: Enzyme
Novelty: 0.9065415
p_int: 0.85136088
p_ni: 0.148638876
p_wrong: 2.44e-7
Score: 0.214
Data Source: BioPlex,STRINGDB
GNPNAT1
Family: Enzyme
Novelty: 0.01739665
p_int: 0.787991045
p_ni: 0.00238879
p_wrong: 0.209620164
Score: 0.23
Data Source: BioPlex,STRINGDB
GALM
Family: Enzyme
Novelty: 0.01067063
p_int: 0.76540896
p_ni: 0.234591009
p_wrong: 3.1e-8
Score: 0.455
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (7)
Reactome (5)
KEGG (1)
WikiPathways (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | G alpha (s) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | Olfactory Signaling Pathway | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by GPCR | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
G alpha (s) signalling events | ||||
GPCR downstream signalling | ||||
Olfactory Signaling Pathway | ||||
Signal Transduction | ||||
Signaling by GPCR | ||||
Viral Interactions (0)
Gene Ontology Terms (7)
Functions (3)
Components (2)
Processes (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations (null)
GWAS Traits (2)
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 1 | 1 | 1 | 38.2 | |||||
body height | 1 | 1 | 1 | 2.9 | |||||
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 1 | 38.2 | |||||
body height | 1 | 2.9 | |||||
Find similar targets by:
IDG Resources
Orthologs (3)
1 – 3 of 3
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Cow | olfactory receptor, family 5, subfamily F, member 1 | 785930 | ||||||
Opossum | olfactory receptor 5F1-like | 100022796 | ||||||
Anole lizard | olfactory receptor 5F1-like | 100553036 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Cow | olfactory receptor, family 5, subfamily F, member 1 | |||||
Opossum | olfactory receptor 5F1-like | |||||
Anole lizard | olfactory receptor 5F1-like | |||||
Publication Statistics
PubMed Score 0.09
PubMed score by year
PubTator Score 0.33
PubTator score by year
Patents
Patents by year
Related Publications
Text Mined References (5)
Items per page:
0 of 0
PMID | Year | Title |
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