OR51E1
Olfactory receptor 51E1
Protein Summary
Odorant receptor. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
- ENST00000396952
- ENSP00000380155
- ENSG00000180785
- GPR164
- OR51E1P
- OR52A3P
- POGR
- PSGR2
- POGR
- DGPCR
- PSGR2
- D-GPCR
- GPR136
- GPR164
- OR51E1P
- OR52A3P
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
microRNA | 0.64 | ||
cell line | 0.51 | ||
tissue | 0.49 | ||
tissue sample | 0.48 | ||
trait | 0.46 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 23.5 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 174 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 23.5 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 174 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (38)
Nearest Tclin Targets
Pathways (6)
Reactome (5)
KEGG (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | G alpha (s) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | Olfactory Signaling Pathway | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by GPCR | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
G alpha (s) signalling events | ||||
GPCR downstream signalling | ||||
Olfactory Signaling Pathway | ||||
Signal Transduction | ||||
Signaling by GPCR | ||||
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (2)
Components (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations (null)
GWAS Traits (4)
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1 – 4 of 4
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
monocyte count | 1 | 1 | 1 | 53.3 | |||||
diastolic blood pressure | 1 | 1 | 1 | 44.2 | |||||
smoking behavior | 1 | 1 | 1 | 17.8 | |||||
monocyte percentage of leukocytes | 1 | 1 | 1 | 5.9 | |||||
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
monocyte count | 1 | 53.3 | |||||
diastolic blood pressure | 1 | 44.2 | |||||
smoking behavior | 1 | 17.8 | |||||
monocyte percentage of leukocytes | 1 | 5.9 | |||||
Find similar targets by:
IDG Resources
Orthologs (8)
1 – 5 of 8
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Macaque | olfactory receptor 51E1 | 717598 | ||||||
Mouse | MGI:3030392 | 259097 | ||||||
Rat | RGD:1332833 | 365323 | ||||||
Dog | olfactory receptor 51E1 | 485235 | ||||||
Horse | olfactory receptor family 51 subfamily E member 1 | VGNC:54743 | 100067037 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Macaque | olfactory receptor 51E1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | olfactory receptor 51E1 | |||||
Horse | olfactory receptor family 51 subfamily E member 1 | |||||
Publication Statistics
PubMed Score 23.50
PubMed score by year
PubTator Score 8.97
PubTator score by year
Patents
Patents by year
Related Publications
Text Mined References (14)
GeneRif Annotations (7)
Items per page:
0 of 0
PMID | Year | Title |
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