You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
OR2G6
Olfactory receptor 2G6

Protein Summary
Description
Odorant receptor. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000343414
  • ENSP00000341291
  • ENSG00000188558
  • ENST00000641501
  • ENSP00000492940
  • ENST00000641804
  • ENSP00000493355
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.79
cell line
0.7
PubMedID
0.54
protein domain
0.41
pathway
0.32


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 67   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 67   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
UBB
Tbio
Novelty:  0.00661254
p_int:  0.999912792
p_ni:  0.000079655
p_wrong:  0.000007554
Data Source:  BioPlex
SLC44A5
Tdark
Family:  Transporter
Novelty:  0.15262166
p_int:  0.999191914
p_ni:  0.000334052
p_wrong:  0.000474034
Data Source:  BioPlex
UBL7
Tbio
Novelty:  0.20935024
p_int:  0.99730014
p_ni:  0.000068954
p_wrong:  0.002630906
Data Source:  BioPlex
DPY19L4
Tdark
Family:  Enzyme
Novelty:  0.99997412
p_int:  0.997073964
p_ni:  0.002922881
p_wrong:  0.000003155
Data Source:  BioPlex
MINDY1
Tbio
Novelty:  0.31540765
p_int:  0.993357908
p_ni:  0.005518061
p_wrong:  0.001124031
Data Source:  BioPlex
SLC12A4
Tbio
Family:  Transporter
Novelty:  0.01077688
p_int:  0.989819064
p_ni:  0.010170131
p_wrong:  0.000010805
Data Source:  BioPlex
KIAA1549
Tbio
Novelty:  0.01224835
p_int:  0.987515532
p_ni:  0.012484048
p_wrong:  4.2e-7
Data Source:  BioPlex
PLAA
Tchem
Family:  Enzyme
Novelty:  0.01164687
p_int:  0.984705308
p_ni:  0.015294692
Data Source:  BioPlex
ATP2B4
Tbio
Family:  Transporter
Novelty:  0.00560356
p_int:  0.947356365
p_ni:  0.052643609
p_wrong:  2.6e-8
Data Source:  BioPlex
TAX1BP1
Tbio
Novelty:  0.02498501
p_int:  0.942029603
p_ni:  0.057970397
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (6)
G alpha (s) signalling events (R-HSA-418555)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
G alpha (s) signalling events
Reactome
GPCR downstream signalling
Reactome
Olfactory Signaling Pathway
Reactome
Signal Transduction
Reactome
Signaling by GPCR
Name
Explore in Pharos
Explore in Source
G alpha (s) signalling events
GPCR downstream signalling
Olfactory Signaling Pathway
Signal Transduction
Signaling by GPCR
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Opossum
olfactory receptor 2G6-like
100619275
Species
Name
OMA
EggNOG
Inparanoid
Opossum
olfactory receptor 2G6-like
Publication Statistics
PubMed Score 0.11
PubMed score by year
Patents
Patents by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title