Protein Summary
Odorant receptor. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
- ENST00000531945
- ENSP00000431914
- ENSG00000196248
- OR11-279
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell line | 0.55 | ||
protein domain | 0.41 | ||
tissue | 0.39 | ||
pathway | 0.32 | ||
tissue sample | 0.31 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.46 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 109 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.46 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 109 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (51)
SLC12A6
Family: Transporter
Novelty: 0.0132619
p_int: 0.995678789
p_ni: 0.004299787
p_wrong: 0.000021424
Data Source: BioPlex
SLC12A4
Family: Transporter
Novelty: 0.01077688
p_int: 0.993291418
p_ni: 0.006706913
p_wrong: 0.00000167
Data Source: BioPlex
MINDY1
Novelty: 0.31540765
p_int: 0.97693254
p_ni: 0.022831858
p_wrong: 0.000235601
Data Source: BioPlex
SLC44A5
Family: Transporter
Novelty: 0.15262166
p_int: 0.903650029
p_ni: 0.002565347
p_wrong: 0.093784623
Data Source: BioPlex
ABCC4
Family: Transporter
Novelty: 0.00208051
p_int: 0.880305189
p_ni: 0.119648691
p_wrong: 0.00004612
Data Source: BioPlex
CYP51A1
Family: Enzyme
Novelty: 0.00127373
p_int: 0.878935735
p_ni: 0.121064265
Data Source: BioPlex
ZFAND2B
Novelty: 0.28286118
p_int: 0.878534442
p_ni: 0.000046449
p_wrong: 0.121419108
Data Source: BioPlex
EMC3
Novelty: 0.01113829
p_int: 0.831628289
p_ni: 0.125730068
p_wrong: 0.042641642
Data Source: BioPlex
PIGO
Family: Enzyme
Novelty: 0.05949164
p_int: 0.809248232
p_ni: 0.190751768
Data Source: BioPlex
Nearest Tclin Targets
Pathways (6)
Reactome (5)
KEGG (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | G alpha (s) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | Olfactory Signaling Pathway | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by GPCR | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
G alpha (s) signalling events | ||||
GPCR downstream signalling | ||||
Olfactory Signaling Pathway | ||||
Signal Transduction | ||||
Signaling by GPCR | ||||
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (2)
Components (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations (null)
GWAS Traits (0)
Find similar targets by:
IDG Resources
Orthologs (5)
1 – 5 of 5
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Mouse | MGI:3030816 | 258853 | ||||||
Dog | olfactory receptor, family 10, subfamily S, member 1 | 100688600 | ||||||
Horse | olfactory receptor family 10 subfamily S member 1 | VGNC:54681 | 100071816 | |||||
Pig | olfactory receptor 10S1 | 100512247 | ||||||
Opossum | olfactory receptor 10S1-like | 100030353 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Mouse | ||||||
Dog | olfactory receptor, family 10, subfamily S, member 1 | |||||
Horse | olfactory receptor family 10 subfamily S member 1 | |||||
Pig | olfactory receptor 10S1 | |||||
Opossum | olfactory receptor 10S1-like | |||||
Publication Statistics
PubMed Score 0.46
PubMed score by year
Patents
Patents by year
Related Publications
Text Mined References (4)
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