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Tdark
OR10S1
Olfactory receptor 10S1

Protein Summary
Description
Odorant receptor. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000531945
  • ENSP00000431914
  • ENSG00000196248

Symbol
  • OR11-279
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.55
protein domain
0.41
tissue
0.39
pathway
0.32
tissue sample
0.31


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (51)
SLC12A6
Tbio
Family:  Transporter
Novelty:  0.0132619
p_int:  0.995678789
p_ni:  0.004299787
p_wrong:  0.000021424
Data Source:  BioPlex
SLC12A4
Tbio
Family:  Transporter
Novelty:  0.01077688
p_int:  0.993291418
p_ni:  0.006706913
p_wrong:  0.00000167
Data Source:  BioPlex
MINDY1
Tbio
Novelty:  0.31540765
p_int:  0.97693254
p_ni:  0.022831858
p_wrong:  0.000235601
Data Source:  BioPlex
SLC44A5
Tdark
Family:  Transporter
Novelty:  0.15262166
p_int:  0.903650029
p_ni:  0.002565347
p_wrong:  0.093784623
Data Source:  BioPlex
ABCC4
Tchem
Family:  Transporter
Novelty:  0.00208051
p_int:  0.880305189
p_ni:  0.119648691
p_wrong:  0.00004612
Data Source:  BioPlex
CYP51A1
Tchem
Family:  Enzyme
Novelty:  0.00127373
p_int:  0.878935735
p_ni:  0.121064265
Data Source:  BioPlex
ZFAND2B
Tbio
Novelty:  0.28286118
p_int:  0.878534442
p_ni:  0.000046449
p_wrong:  0.121419108
Data Source:  BioPlex
EMC3
Tbio
Novelty:  0.01113829
p_int:  0.831628289
p_ni:  0.125730068
p_wrong:  0.042641642
Data Source:  BioPlex
PIGO
Tbio
Family:  Enzyme
Novelty:  0.05949164
p_int:  0.809248232
p_ni:  0.190751768
Data Source:  BioPlex
DNAJB4
Tbio
Novelty:  0.03467352
p_int:  0.797430003
p_ni:  0.202569997
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (6)
G alpha (s) signalling events (R-HSA-418555)

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Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
G alpha (s) signalling events
Reactome
GPCR downstream signalling
Reactome
Olfactory Signaling Pathway
Reactome
Signal Transduction
Reactome
Signaling by GPCR
Name
Explore in Pharos
Explore in Source
G alpha (s) signalling events
GPCR downstream signalling
Olfactory Signaling Pathway
Signal Transduction
Signaling by GPCR
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3030816
258853
Dog
olfactory receptor, family 10, subfamily S, member 1
100688600
Horse
olfactory receptor family 10 subfamily S member 1
VGNC:54681
100071816
Pig
olfactory receptor 10S1
100512247
Opossum
olfactory receptor 10S1-like
100030353
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Dog
olfactory receptor, family 10, subfamily S, member 1
Horse
olfactory receptor family 10 subfamily S member 1
Pig
olfactory receptor 10S1
Opossum
olfactory receptor 10S1-like
Publication Statistics
PubMed Score 0.46
PubMed score by year
Patents
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Related Publications
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0 of 0
PMID
Year
Title