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Tdark
OPALIN
Opalin

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371172
  • ENSP00000360214
  • ENSG00000197430
  • ENST00000393871
  • ENSP00000377449
  • ENST00000419479
  • ENSP00000398025
  • ENST00000611913
  • ENSP00000484599

Symbol
  • HTMP10
  • TMEM10
  • TMP10
  • HTMP10
  • TMEM10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.93
microRNA
0.58
tissue
0.57
cellular component
0.54
cell line
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.33   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.33   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (214)
ATP2B3
Tbio
Family:  Transporter
Novelty:  0.00901493
p_int:  0.999990096
p_ni:  0.000009904
Score:  0.531
Data Source:  BioPlex,STRINGDB
UTP20
Tbio
Novelty:  0.09170451
p_int:  0.999972505
p_ni:  0.000027494
p_wrong:  1e-9
Data Source:  BioPlex
SMAD5
Tbio
Family:  TF
Novelty:  0.00405952
p_int:  0.999966372
p_ni:  0.000030457
p_wrong:  0.000003171
Data Source:  BioPlex
ATP2B4
Tbio
Family:  Transporter
Novelty:  0.00560356
p_int:  0.999948669
p_ni:  0.000051329
p_wrong:  2e-9
Data Source:  BioPlex
NF1
Tbio
Novelty:  0.00019092
p_int:  0.99993708
p_ni:  0.00006292
Data Source:  BioPlex
RTTN
Tbio
Novelty:  0.04524944
p_int:  0.999921894
p_ni:  0.000002525
p_wrong:  0.000075581
Data Source:  BioPlex
BTAF1
Tbio
Novelty:  0.01586704
p_int:  0.999895436
p_ni:  0.000104564
Data Source:  BioPlex
ATP2B2
Tbio
Family:  Transporter
Novelty:  0.007782
p_int:  0.999877492
p_ni:  0.000122508
Score:  0.531
Data Source:  BioPlex,STRINGDB
ATR
Tchem
Family:  Kinase
Novelty:  0.00196978
p_int:  0.999867212
p_ni:  0.000132788
Data Source:  BioPlex
THADA
Tbio
Novelty:  0.06983966
p_int:  0.999825423
p_ni:  0.000174577
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
1
1
35.6
gut microbiome measurement
1
1
1
31.7
aging
1
1
1
30.6
educational attainment
1
1
1
27.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
35.6
gut microbiome measurement
1
31.7
aging
1
30.6
educational attainment
1
27.1
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
oligodendrocytic myelin paranodal and inner loop protein
VGNC:5587
450643
Macaque
oligodendrocytic myelin paranodal and inner loop protein
704725
Mouse
MGI:2657025
226115
Rat
RGD:1307776
361757
Dog
oligodendrocytic myelin paranodal and inner loop protein
VGNC:44127
608634
Species
Name
OMA
EggNOG
Inparanoid
Chimp
oligodendrocytic myelin paranodal and inner loop protein
Macaque
oligodendrocytic myelin paranodal and inner loop protein
Mouse
Rat
Dog
oligodendrocytic myelin paranodal and inner loop protein
Publication Statistics
PubMed Score 13.33
PubMed score by year
PubTator Score 11.60
PubTator score by year
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Related Publications
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PMID
Year
Title