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Tdark
OGFOD2
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000228922
  • ENSP00000228922
  • ENSG00000111325
  • ENST00000397389
  • ENSP00000380544
  • ENST00000454694
  • ENSP00000394175
  • ENST00000536150
  • ENSP00000438327
  • ENST00000538628
  • ENSP00000444608
  • ENST00000538755
  • ENSP00000442817
  • ENST00000540324
  • ENSP00000439667
  • ENST00000545317
  • ENSP00000438192
  • ENST00000545612
  • ENSP00000444436
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.87
transcription factor binding site profile
0.8
molecular function
0.7
tissue sample
0.7
cellular component
0.69


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.35   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 114   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.35   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
ABCB9
Tbio
Family:  Transporter
Novelty:  0.02217672
Score:  0.821
Data Source:  STRINGDB
OGFOD1
Tbio
Family:  Enzyme
Novelty:  0.023983
Score:  0.749
Data Source:  STRINGDB
HSPBAP1
Tbio
Novelty:  0.03321047
Score:  0.743
Data Source:  STRINGDB
KHNYN
Tdark
Novelty:  0.34058138
Score:  0.726
Data Source:  STRINGDB
KDM8
Tbio
Family:  Epigenetic
Novelty:  0.03368031
Score:  0.703
Data Source:  STRINGDB
RIOX1
Tbio
Family:  Epigenetic
Novelty:  0.06360414
Score:  0.698
Data Source:  STRINGDB
P3H1
Tbio
Family:  Enzyme
Novelty:  0.02067711
Score:  0.64
Data Source:  STRINGDB
YJEFN3
Tdark
Novelty:  1.37195122
Score:  0.639
Data Source:  STRINGDB
P4HTM
Tchem
Family:  Enzyme
Novelty:  0.00582577
Score:  0.619
Data Source:  STRINGDB
HIF1AN
Tbio
Novelty:  0.00861018
Score:  0.598
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (20)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
4
5
8
90.8
type 2 diabetes mellitus
3
3
2
1.1
88.4
calcium measurement
3
1
3
84.3
schizophrenia
1
1
0
1.1
79
educational attainment
2
2
1
66.5
74.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
8
90.8
type 2 diabetes mellitus
2
1.1
88.4
calcium measurement
3
84.3
schizophrenia
0
1.1
79
educational attainment
1
66.5
74.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
2-oxoglutarate and iron dependent oxygenase domain containing 2
VGNC:8478
744854
Macaque
2-oxoglutarate and iron dependent oxygenase domain containing 2
703753
Mouse
MGI:1913877
66627
Rat
RGD:1310594
288657
Dog
2-oxoglutarate and iron dependent oxygenase domain containing 2
VGNC:44106
477455
Species
Name
OMA
EggNOG
Inparanoid
Chimp
2-oxoglutarate and iron dependent oxygenase domain containing 2
Macaque
2-oxoglutarate and iron dependent oxygenase domain containing 2
Mouse
Rat
Dog
2-oxoglutarate and iron dependent oxygenase domain containing 2
Publication Statistics
PubMed Score 1.35
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title