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Tdark
OCEL1
Occludin/ELL domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000215061
  • ENSP00000215061
  • ENSG00000099330

Symbol
  • FWP009
  • S863-9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.76
disease perturbation
0.74
transcription factor
0.69
transcription factor binding site profile
0.66
cell type or tissue
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.45   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 79   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.45   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (20)
FAM217B
Tdark
Novelty:  4.03122155
Score:  0.734
Data Source:  STRINGDB
FICD
Tbio
Family:  Enzyme
Novelty:  0.01131805
Score:  0.656
Data Source:  STRINGDB
TMEM205
Tdark
Novelty:  0.41048198
Score:  0.65
Data Source:  STRINGDB
METTL7B
Tbio
Family:  Enzyme
Novelty:  0.0873748
Score:  0.597
Data Source:  STRINGDB
ABHD8
Tdark
Family:  Enzyme
Novelty:  0.27752967
Score:  0.575
Data Source:  STRINGDB
RAB2B
Tbio
Family:  Enzyme
Novelty:  0.18567584
Score:  0.55
Data Source:  STRINGDB
PPP1R3D
Tdark
Family:  Enzyme
Novelty:  0.53609018
Score:  0.548
Data Source:  STRINGDB
MYO9B
Tbio
Novelty:  0.0164265
Score:  0.528
Data Source:  STRINGDB
RAB13
Tbio
Family:  Enzyme
Novelty:  0.02465609
Score:  0.501
Data Source:  STRINGDB
IDI2
Tbio
Family:  Enzyme
Novelty:  0.02715208
Score:  0.498
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (27)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
6
4
0
1.2
98.5
mitochondrial DNA measurement
3
5
5
97.8
HbA1c measurement
5
9
9
97.6
2
3
0
1.2
96.8
testosterone measurement
5
3
5
94.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
98.5
mitochondrial DNA measurement
5
97.8
HbA1c measurement
9
97.6
0
1.2
96.8
testosterone measurement
5
94.9
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
occludin/ELL domain containing 1
VGNC:7564
455823
Macaque
occludin/ELL domain containing 1
718921
Mouse
MGI:1924340
77090
Rat
RGD:1565407
290628
Dog
occludin/ELL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26221]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
occludin/ELL domain containing 1
Macaque
occludin/ELL domain containing 1
Mouse
Rat
Dog
occludin/ELL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26221]
Publication Statistics
PubMed Score 2.45
PubMed score by year
PubTator Score 0.70
PubTator score by year
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Related Publications
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PMID
Year
Title