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Tbio
TOMM40
Mitochondrial import receptor subunit TOM40 homolog

Protein Summary
Description
Channel-forming protein essential for import of protein precursors into mitochondria. The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000252487
  • ENSP00000252487
  • ENSG00000130204
  • ENST00000405636
  • ENSP00000385184
  • ENST00000426677
  • ENSP00000410339
  • ENST00000592434
  • ENSP00000466084

Symbol
  • C19orf1
  • PEREC1
  • TOM40
  • TOM40
  • PEREC1
  • C19orf1
  • PER-EC1
  • D19S1177E
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
1
disease perturbation
0.93
histone modification site profile
0.89
phenotype
0.89
transcription factor binding site profile
0.89


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 271.22   (req: < 5)
Gene RIFs: 96   (req: <= 3)
Antibodies: 131   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 271.22   (req: >= 5)
Gene RIFs: 96   (req: > 3)
Antibodies: 131   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0