TOMM40
Mitochondrial import receptor subunit TOM40 homolog
Protein Summary
Channel-forming protein essential for import of protein precursors into mitochondria. The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]
- ENST00000252487
- ENSP00000252487
- ENSG00000130204
- ENST00000405636
- ENSP00000385184
- ENST00000426677
- ENSP00000410339
- ENST00000592434
- ENSP00000466084
- C19orf1
- PEREC1
- TOM40
- TOM40
- PEREC1
- C19orf1
- PER-EC1
- D19S1177E
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
trait | 1 | ||
disease perturbation | 0.93 | ||
histone modification site profile | 0.89 | ||
phenotype | 0.89 | ||
transcription factor binding site profile | 0.89 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 271.22 (req: < 5)
Gene RIFs: 96 (req: <= 3)
Antibodies: 131 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 271.22 (req: >= 5)
Gene RIFs: 96 (req: > 3)
Antibodies: 131 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0