GAS8
Dynein regulatory complex subunit 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
tissue sample | 0.62 | ||
disease perturbation | 0.56 | ||
histone modification site profile | 0.55 | ||
small molecule perturbation | 0.5 | ||
phenotype | 0.49 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of SMO | ||||
Reactome | Hedgehog 'on' state | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by Hedgehog | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of SMO | ||||
Hedgehog 'on' state | ||||
Signal Transduction | ||||
Signaling by Hedgehog | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hair color | 9 | 17 | 1 | 2.5 | 99.9 | ||||
suntan | 3 | 9 | 9 | 99.8 | |||||
1 | 3 | 0 | 1.5 | 97.9 | |||||
4 | 3 | 2 | 1.4 | 97.5 | |||||
3 | 3 | 0 | 1.3 | 96.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hair color | 1 | 2.5 | 99.9 | ||||
suntan | 9 | 99.8 | |||||
0 | 1.5 | 97.9 | |||||
2 | 1.4 | 97.5 | |||||
0 | 1.3 | 96.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | growth arrest specific 8 | VGNC:5775 | 454330 | |||||
Macaque | growth arrest specific 8 | 701458 | ||||||
Mouse | MGI:1202386 | 104346 | ||||||
Rat | RGD:1307817 | 361438 | ||||||
Dog | growth arrest specific 8 | VGNC:41120 | 608663 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | growth arrest specific 8 | |||||
Macaque | growth arrest specific 8 | |||||
Mouse | ||||||
Rat | ||||||
Dog | growth arrest specific 8 | |||||
PMID | Year | Title |
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