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Tbio
ITGBL1
Integrin beta-like protein 1

Protein Classes
Protein Summary
Description
This gene encodes a beta integrin-related protein that is a member of the EGF-like protein family. The encoded protein contains integrin-like cysteine-rich repeats. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000376162
  • ENSP00000365332
  • ENSG00000198542
  • ENST00000376180
  • ENSP00000365351
  • ENST00000545560
  • ENSP00000439903

Symbol
  • OSCP
  • TIED
  • OSCP
  • TIED
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.99
gene perturbation
0.94
co-expressed gene
0.91
tissue sample
0.72
PubMedID
0.68


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.04   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.04   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
integrin subunit beta like 1
VGNC:5070
467314
Macaque
integrin subunit beta like 1
700965
Mouse
MGI:2443439
223272
Rat
RGD:1560635
498564
Dog
integrin subunit beta like 1
VGNC:42144
485536
Species
Name
OMA
EggNOG
Inparanoid
Chimp
integrin subunit beta like 1
Macaque
integrin subunit beta like 1
Mouse
Rat
Dog
integrin subunit beta like 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O95965-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (6)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Reactome
RUNX2 regulates genes involved in cell migration
Reactome
Transcriptional regulation by RUNX2
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
RUNX2 regulates genes involved in cell migration
Transcriptional regulation by RUNX2
Gene Ontology Terms (11)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (61)
1 – 10 of 61
CBFB
Tchem
Family:  TF
Novelty:  0.04825679
Score:  0.9
Data Source:  STRINGDB
ITGA11
Tbio
Novelty:  0.02501472
Score:  0.698
Data Source:  STRINGDB
ITGAD
Tbio
Novelty:  0.01613546
Score:  0.667
Data Source:  STRINGDB
ITGA9
Tbio
Novelty:  0.01488635
Score:  0.662
Data Source:  STRINGDB
ITGA7
Tbio
Novelty:  0.01243073
Score:  0.661
Data Source:  STRINGDB
ITGA10
Tbio
Novelty:  0.03550593
Score:  0.636
Data Source:  STRINGDB
ITGA5
Tbio
Novelty:  0.00285802
Score:  0.616
Data Source:  STRINGDB
COQ10B
Tdark
Novelty:  0.59492584
Score:  0.605
Data Source:  STRINGDB
ITGA8
Tbio
Novelty:  0.0220023
Score:  0.602
Data Source:  STRINGDB
ITGA3
Tchem
Novelty:  0.00505981
Score:  0.601
Data Source:  STRINGDB
Publication Statistics
PubMed Score  30.04

PubMed score by year
PubTator Score  11.27

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer