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Tdark
GPANK1
G patch domain and ankyrin repeat-containing protein 1

Protein Summary
Description
This gene is located in a cluster of HLA-B-associated transcripts, which is included in the human major histocompatability complex III region. This gene encodes a protein which is thought to play a role in immunity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000211377
  • ENSP00000211377
  • ENSG00000236011
  • ENST00000375893
  • ENSP00000365057
  • ENSG00000204438
  • ENST00000375895
  • ENSP00000365059
  • ENST00000375896
  • ENSP00000365060
  • ENST00000375900
  • ENSP00000365065
  • ENST00000375906
  • ENSP00000365071
  • ENST00000383434
  • ENSP00000372926
  • ENSG00000206408
  • ENST00000383436
  • ENSP00000372928
  • ENST00000400129
  • ENSP00000382994
  • ENST00000400134
  • ENSP00000382999
  • ENST00000400139
  • ENSP00000383005
  • ENST00000414528
  • ENSP00000389339
  • ENSG00000228605
  • ENST00000416384
  • ENSP00000401376
  • ENSG00000223932
  • ENST00000417890
  • ENSP00000415855
  • ENSG00000232312
  • ENST00000418502
  • ENSP00000412321
  • ENST00000422131
  • ENSP00000410690
  • ENST00000426326
  • ENSP00000398927
  • ENST00000427527
  • ENSP00000391604
  • ENST00000429266
  • ENSP00000412884
  • ENST00000433857
  • ENSP00000406895
  • ENST00000433880
  • ENSP00000401272
  • ENST00000439710
  • ENSP00000409206
  • ENST00000440777
  • ENSP00000399890
  • ENST00000447705
  • ENSP00000403829
  • ENST00000448091
  • ENSP00000411691
  • ENST00000449868
  • ENSP00000393567
  • ENST00000453746
  • ENSP00000390746
  • ENST00000453899
  • ENSP00000413662
  • ENST00000456191
  • ENSP00000401276
  • ENST00000457505
  • ENSP00000406507

Symbol
  • ANKRD59
  • BAT4
  • G5
  • GPATCH10
  • G5
  • BAT4
  • D6S54E
  • ANKRD59
  • GPATCH10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
cellular component
0.72
disease
0.7
tissue sample
0.67
phenotype
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
3
91.5
1
1
0
3
91.5
1
1
0
3
91.5
1
1
0
3
91.5
1
1
0
3
91.5
Items per page:
1 – 5 of 5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
3
91.5
0
3
91.5
0
3
91.5
0
3
91.5
0
3
91.5
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (35)
1 – 10 of 35
TTC19
Tbio
Novelty: 0.08251578
p_int: 0.999992068
p_ni: 0.000007932
Score: 0.21
Data Source: BioPlex,STRINGDB
IL37
Tbio
Novelty: 0.00499186
p_int: 0.97835038
p_ni: 0.021022162
p_wrong: 0.000627458
Score: 0.199
Data Source: BioPlex,STRINGDB
TGM1
Tchem
Family: Enzyme
Novelty: 0.00103799
p_int: 0.830048205
p_ni: 0.169951795
Score: 0.234
Data Source: BioPlex,STRINGDB
ALOX12B
Tbio
Family: Enzyme
Novelty: 0.02778552
p_int: 0.798145824
p_ni: 0.201854176
Score: 0.28
Data Source: BioPlex,STRINGDB
KPRP
Tdark
Novelty: 0.11744927
p_int: 0.764217823
p_ni: 0.234640654
p_wrong: 0.001141523
Score: 0.189
Data Source: BioPlex,STRINGDB
HDGFL3
Tbio
Family: Epigenetic
Novelty: 0.14292821
p_int: 0.751617718
p_ni: 0.000936626
p_wrong: 0.247445655
Score: 0.188
Data Source: BioPlex,STRINGDB
APOM
Tbio
Novelty: 0.00505937
Score: 0.931
Data Source: STRINGDB
ABHD16A
Tchem
Family: Enzyme
Novelty: 0.04797219
Score: 0.883
Data Source: STRINGDB
ZBTB12
Tbio
Family: TF
Novelty: 0.15640131
Score: 0.804
Data Source: STRINGDB
PRRC2A
Tbio
Novelty: 0.01493149
Score: 0.794
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.00

PubMed score by year
PubTator Score  76.07

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer