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Tchem
ABHD16A
Protein ABHD16A

Protein Summary
Description
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is thought to be involved in some aspects of immunity. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000395952
  • ENSP00000379282
  • ENSG00000204427
  • ENST00000440843
  • ENSP00000410347
  • ENST00000446529
  • ENSP00000395665
  • ENSG00000206403
  • ENST00000548592
  • ENSP00000448431
  • ENST00000549722
  • ENSP00000447549
  • ENSG00000230475
  • ENST00000549853
  • ENSP00000447846
  • ENSG00000236063
  • ENST00000550556
  • ENSP00000447498
  • ENSG00000235676
  • ENST00000551038
  • ENSP00000449579
  • ENSG00000231488
  • ENST00000552042
  • ENSP00000448451
  • ENSG00000224552

Symbol
  • BAT5
  • G5
  • NG26
  • BAT5
  • NG26
  • PP199
  • D6S82E
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.87
transcription factor perturbation
0.68
transcription factor
0.63
phenotype
0.61
tissue sample
0.61


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.45   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 89   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.45   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 1
Approved Drugs (1)
1 – 1 of 1
orlistat
chemical structure image
GWAS Traits (12)
Items per page:
1 – 5 of 12
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mosquito bite reaction itch intensity measurement
1
1
1
50.2
mosquito bite reaction itch intensity measurement
1
1
1
50.2
mosquito bite reaction itch intensity measurement
1
1
1
50.2
mosquito bite reaction itch intensity measurement
1
1
1
50.2
mosquito bite reaction itch intensity measurement
1
1
1
50.2
Items per page:
1 – 5 of 12
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mosquito bite reaction itch intensity measurement
1
50.2
mosquito bite reaction itch intensity measurement
1
50.2
mosquito bite reaction itch intensity measurement
1
50.2
mosquito bite reaction itch intensity measurement
1
50.2
mosquito bite reaction itch intensity measurement
1
50.2
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
abhydrolase domain containing 16A
716051
Mouse
MGI:99476
193742
Rat
RGD:1303164
361796
Dog
abhydrolase domain containing 16A
VGNC:37464
474845
Horse
abhydrolase domain containing 16A
VGNC:14941
100058736
Species
Name
OMA
EggNOG
Inparanoid
Macaque
abhydrolase domain containing 16A
Mouse
Rat
Dog
abhydrolase domain containing 16A
Horse
abhydrolase domain containing 16A
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O95870-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
BHF-UCL
Protein-Protein Interactions (95)
1 – 10 of 95
TBC1D9
Tbio
Novelty: 0.20059899
p_int: 0.999997207
p_ni: 0.000002793
Score: 0.208
Data Source: BioPlex,STRINGDB
SCNN1D
Tbio
Family: IC
Novelty: 0.06191685
p_int: 0.999989121
p_ni: 0.000010607
p_wrong: 2.72e-7
Score: 0.187
Data Source: BioPlex,STRINGDB
HTR3C
Tchem
Family: IC
Novelty: 0.112097
p_int: 0.999981188
p_ni: 0.000013957
p_wrong: 0.000004855
Score: 0.196
Data Source: BioPlex,STRINGDB
MCOLN3
Tchem
Family: IC
Novelty: 0.03209262
p_int: 0.996462887
p_ni: 0.000220048
p_wrong: 0.003317065
Score: 0.177
Data Source: BioPlex,STRINGDB
GPANK1
Tdark
Novelty: 0.20285376
Score: 0.883
Data Source: STRINGDB
ZBTB12
Tbio
Family: TF
Novelty: 0.15640131
Score: 0.755
Data Source: STRINGDB
LTA
Tbio
Novelty: 0.00100413
Score: 0.752
Data Source: STRINGDB
PRRC2A
Tbio
Novelty: 0.01493149
Score: 0.748
Data Source: STRINGDB
LST1
Tbio
Novelty: 0.0468696
Score: 0.711
Data Source: STRINGDB
ABHD13
Tdark
Family: Enzyme
Novelty: 2.01646617
Score: 0.663
Data Source: STRINGDB
Publication Statistics
PubMed Score  22.45

PubMed score by year
PubTator Score  9.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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