GGPS1
Geranylgeranyl pyrophosphate synthase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.96 | ||
virus perturbation | 0.85 | ||
histone modification site profile | 0.83 | ||
transcription factor binding site profile | 0.83 | ||
disease perturbation | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of gene expression by SREBF (SREBP) | ||||
Reactome | Cholesterol biosynthesis | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | Metabolism of steroids | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of gene expression by SREBF (SREBP) | ||||
Cholesterol biosynthesis | ||||
Metabolism | ||||
Metabolism of lipids | ||||
Metabolism of steroids | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mathematical ability | 4 | 3 | 4 | 87.3 | |||||
sex hormone-binding globulin measurement | 5 | 2 | 5 | 80.3 | |||||
monocyte percentage of leukocytes | 1 | 1 | 1 | 68.3 | |||||
self reported educational attainment | 1 | 1 | 1 | 66.8 | |||||
2 | 1 | 2 | 49.5 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mathematical ability | 4 | 87.3 | |||||
sex hormone-binding globulin measurement | 5 | 80.3 | |||||
monocyte percentage of leukocytes | 1 | 68.3 | |||||
self reported educational attainment | 1 | 66.8 | |||||
2 | 49.5 | ||||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | geranylgeranyl diphosphate synthase 1 | VGNC:1246 | 100610192 | |||||
Mouse | MGI:1341724 | 14593 | ||||||
Rat | RGD:1359680 | 291211 | ||||||
Dog | geranylgeranyl diphosphate synthase 1 | VGNC:41201 | 479198 | |||||
Horse | geranylgeranyl diphosphate synthase 1 | VGNC:18327 | 100050954 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | geranylgeranyl diphosphate synthase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | geranylgeranyl diphosphate synthase 1 | |||||
Horse | geranylgeranyl diphosphate synthase 1 | |||||
PMID | Year | Title |
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