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Tbio
RAB3D
Ras-related protein Rab-3D

Protein Summary
Description
Protein transport. Probably involved in regulated exocytosis (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000222120
  • ENSP00000222120
  • ENSG00000105514
  • ENST00000589655
  • ENSP00000466000

Symbol
  • GOV
  • RAB16
  • GOV
  • D2-2
  • RAB16
  • RAD3D
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
molecular function
0.96
disease perturbation
0.79
small molecule perturbation
0.78
virus perturbation
0.72


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 119.46   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 149   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 119.46   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 149   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Pathways (7)
Immune System (R-HSA-168256)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Immune System
Reactome
Innate Immune System
Reactome
Metabolism of proteins
Reactome
Neutrophil degranulation
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Immune System
Innate Immune System
Metabolism of proteins
Neutrophil degranulation
Post-translational protein modification
Gene Ontology Terms (23)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (169)
1 – 10 of 169
RAB35
Tbio
Family: Enzyme
Novelty: 0.01514601
Score: 0.974
Data Source: STRINGDB
CHM
Tbio
Family: Enzyme
Novelty: 0.00226278
Score: 0.96
Data Source: STRINGDB
VAMP8
Tbio
Novelty: 0.01083228
Score: 0.944
Data Source: STRINGDB
CHML
Tbio
Family: Enzyme
Novelty: 0.00509709
Score: 0.937
Data Source: STRINGDB
SYNGR1
Tbio
Novelty: 0.08034637
Score: 0.923
Data Source: STRINGDB
RAB34
Tbio
Family: Enzyme
Novelty: 0.03645677
Score: 0.919
Data Source: STRINGDB
RAB34
Tbio
Novelty: 0.03645677
Score: 0.919
Data Source: STRINGDB
PIGR
Tbio
Novelty: 0.0025812
Score: 0.919
Data Source: STRINGDB
RAB37
Tbio
Family: Enzyme
Novelty: 0.07133253
Score: 0.917
Data Source: STRINGDB
DNAJC5
Tbio
Novelty: 0.00091288
Score: 0.917
Data Source: STRINGDB
Publication Statistics
PubMed Score  119.46

PubMed score by year
PubTator Score  767.79

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer