Tdark METTL18 Histidine protein methyltransferase 1 homolog

Protein Summary

Description

Probable histidine methyltransferase.

Uniprot Accession IDs

• O95568
• B2R9T5

Gene Name

• METTL18

Ensembl ID

• ENST00000303469
• ENSP00000307077
• ENSG00000171806
• ENST00000310392
• ENSP00000307975

Symbol

• ASTP2
• C1orf156
• HPM1
• AsTP2
• C1orf156

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.92
disease perturbation	0.79
transcription factor binding site profile	0.77
cell type or tissue	0.62
tissue sample	0.59

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.9   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 38   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.9   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 38   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0