Protein Summary
NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001 [PubMed 11594753]).[supplied by OMIM, Mar 2008]
- ENST00000341426
- ENSP00000341679
- ENSG00000008130
- ENST00000341991
- ENSP00000344340
- ENST00000378625
- ENSP00000367890
- dJ283E3.1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.99 | ||
molecular function | 0.93 | ||
transcription factor binding site profile | 0.89 | ||
kinase perturbation | 0.84 | ||
transcription factor | 0.78 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 36.22 (req: < 5)
Gene RIFs: 6 (req: <= 3)
Antibodies: 138 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 36.22 (req: >= 5)
Gene RIFs: 6 (req: > 3)
Antibodies: 138 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 8
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (71)
RBM42
Novelty: 0.37655036
p_int: 0.905739651
p_ni: 0.094260349
Score: 0.243
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets (1)
Upstream (1)
1 – 1 of 1
Pathways (9)
Reactome (4)
KEGG (2)
PathwayCommons (2)
WikiPathways (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of vitamins and cofactors | ||||
Reactome | Metabolism of water-soluble vitamins and cofactors | ||||
Reactome | Nicotinate metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Metabolism | ||||
Metabolism of vitamins and cofactors | ||||
Metabolism of water-soluble vitamins and cofactors | ||||
Nicotinate metabolism | ||||
Viral Interactions (0)
Gene Ontology Terms (9)
Functions (3)
Components (1)
Processes (5)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (6)
Items per page:
1 – 5 of 6
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
body mass index | 4 | 3 | 4 | 86.8 | |||||
body height | 1 | 1 | 1 | 61.4 | |||||
reticulocyte count | 1 | 1 | 1 | 38.8 | |||||
reticulocyte measurement | 1 | 1 | 1 | 35 | |||||
electrocardiography | 1 | 1 | 3 | 28.1 | |||||
Items per page:
1 – 5 of 6
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
body mass index | 4 | 86.8 | |||||
body height | 1 | 61.4 | |||||
reticulocyte count | 1 | 38.8 | |||||
reticulocyte measurement | 1 | 35 | |||||
electrocardiography | 3 | 28.1 | |||||
Find similar targets by:
IDG Resources
Orthologs (9)
1 – 5 of 9
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Macaque | NAD kinase | 708852 | ||||||
Mouse | MGI:2183149 | 192185 | ||||||
Rat | RGD:1642420 | 100125370 | ||||||
Dog | NAD kinase | VGNC:43605 | 489589 | |||||
Horse | NAD kinase | VGNC:20543 | 100061432 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Macaque | NAD kinase | |||||
Mouse | ||||||
Rat | ||||||
Dog | NAD kinase | |||||
Horse | NAD kinase | |||||
Publication Statistics
PubMed Score 36.22
PubMed score by year
PubTator Score 55.24
PubTator score by year
Related Publications
Text Mined References (24)
GeneRif Annotations (6)
Items per page:
0 of 0
PMID | Year | Title |
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