Tbio NADK NAD kinase

Protein Summary

Description

NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001 [PubMed 11594753]).[supplied by OMIM, Mar 2008]

Uniprot Accession IDs

• O95544
• A6NNN3
• A8K296
• B7Z434
• F5GXR5
• Q5QPS4
• Q9H2P2
• Q9H931

Gene Name

• NADK

Ensembl ID

• ENST00000341426
• ENSP00000341679
• ENSG00000008130
• ENST00000341991
• ENSP00000344340
• ENST00000378625
• ENSP00000367890

Symbol

• dJ283E3.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.99
molecular function	0.93
transcription factor binding site profile	0.89
kinase perturbation	0.84
transcription factor	0.78

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Nucleotide Kinase / Nad Kinase

DTO Classes

Protein / Kinase / Unclassified Protein / Nad Kinase

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.29   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 138   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.29   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 138   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0