Tbio SLC2A10 Solute carrier family 2, facilitated glucose transporter member 10

Protein Summary

Description

Facilitative glucose transporter. This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.[provided by RefSeq, Dec 2009]

Uniprot Accession IDs

• O95528
• A8K4J6
• Q3MIX5
• Q9H4I6

Gene Name

• SLC2A10

Ensembl ID

• ENST00000359271
• ENSP00000352216
• ENSG00000197496

Symbol

• GLUT10
• ATS
• ATORS
• GLUT10

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.8
tissue sample	0.63
molecular function	0.6
protein domain	0.58
histone modification site profile	0.57

Protein Classes

PANTHER Classes

Protein / ... / Carbohydrate Transporter / Solute Carrier Family 2, Facilitated Glucose Transporter Member 10

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc2 Family Of Hexose And Sugar Alcohol Transporters / Class Ii Transporters / Solute Carrier Family 2, Facilitated Glucose Transporter Member 10

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.83   (req: < 5)

Gene RIFs: 25   (req: <= 3)

Antibodies: 142   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.83   (req: >= 5)

Gene RIFs: 25   (req: > 3)

Antibodies: 142   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0