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Tdark
LCA5L
Lebercilin-like protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000288350
  • ENSP00000288350
  • ENSG00000157578
  • ENST00000358268
  • ENSP00000351008
  • ENST00000380671
  • ENSP00000370046

Symbol
  • C21orf13
  • C21orf13
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.82
tissue sample
0.63
histone modification site profile
0.49
tissue
0.49
transcription factor binding site profile
0.48


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.62   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 114   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.62   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
3
2
3
76.5
apolipoprotein B measurement
1
1
1
66.8
platelet crit
2
2
2
53.2
Non-accomodative esotropia
1
1
0
1.4
44.2
testosterone measurement
1
1
1
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
3
76.5
apolipoprotein B measurement
1
66.8
platelet crit
2
53.2
Non-accomodative esotropia
0
1.4
44.2
testosterone measurement
1
35
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
LCA5L, lebercilin like
VGNC:10510
474116
Macaque
LCA5L, lebercilin like
715569
Mouse
MGI:3041157
385668
Rat
RGD:1562512
498065
Horse
LCA5L, lebercilin like
VGNC:19605
100059350
Species
Name
OMA
EggNOG
Inparanoid
Chimp
LCA5L, lebercilin like
Macaque
LCA5L, lebercilin like
Mouse
Rat
Horse
LCA5L, lebercilin like
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O95447-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (22)
1 – 10 of 22
PCM1
Tbio
Novelty:  0.02901589
p_int:  0.974974948
p_ni:  0.025025052
Score:  0.326
Data Source:  BioPlex,STRINGDB
PFDN5
Tbio
Novelty:  0.07673574
Score:  0.692
Data Source:  STRINGDB
PSMG1
Tbio
Novelty:  0.08175356
Score:  0.636
Data Source:  STRINGDB
SH3BGR
Tbio
Novelty:  0.19912265
Score:  0.63
Data Source:  STRINGDB
DSCR4
Tdark
Novelty:  0.06035045
Score:  0.589
Data Source:  STRINGDB
DSCR8
Tdark
Novelty:  0.06450969
Score:  0.566
Data Source:  STRINGDB
WRB
Tbio
Novelty:  0.01267171
Score:  0.56
Data Source:  STRINGDB
BRWD1
Tbio
Family:  Epigenetic
Novelty:  0.09247334
Score:  0.554
Data Source:  STRINGDB
KRTAP21-2
Tdark
Novelty:  0.86372091
Score:  0.551
Data Source:  STRINGDB
RSPH1
Tbio
Novelty:  0.02982525
Score:  0.537
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.62

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer