Protein Summary
Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
- ENST00000375916
- ENSP00000365081
- ENSG00000204444
- ENST00000375920
- ENSP00000365085
- ENST00000383438
- ENSP00000372930
- ENSG00000206409
- ENST00000400157
- ENSP00000383021
- ENST00000416324
- ENSP00000393581
- ENSG00000224290
- ENST00000422771
- ENSP00000392021
- ENSG00000226215
- ENST00000425177
- ENSP00000403062
- ENSG00000235754
- ENST00000426800
- ENSP00000405730
- ENSG00000227567
- ENST00000430282
- ENSP00000401684
- ENST00000432598
- ENSP00000389591
- ENST00000436931
- ENSP00000394610
- ENSG00000231974
- ENST00000439902
- ENSP00000413446
- ENST00000441436
- ENSP00000398944
- ENST00000443975
- ENSP00000416335
- G3A
- NG20
- G3a
- NG20
- apo-M
- HSPC336
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.9 | ||
histone modification site profile | 0.76 | ||
cellular component | 0.73 | ||
disease | 0.71 | ||
transcription factor perturbation | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 261.91 (req: < 5)
Gene RIFs: 92 (req: <= 3)
Antibodies: 486 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 261.91 (req: >= 5)
Gene RIFs: 92 (req: > 3)
Antibodies: 486 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 13
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (112)
CT45A2
Novelty: 0.98875916
p_int: 0.999938361
p_ni: 0.000061638
Score: 0.689
Data Source: BioPlex,STRINGDB
USP16
Family: Enzyme
Novelty: 0.13211126
p_int: 0.999711318
p_ni: 0.000288637
p_wrong: 4.5e-8
Score: 0.345
Data Source: BioPlex,STRINGDB
SEC11C
Family: Enzyme
Novelty: 0.19577003
p_int: 0.996747856
p_ni: 0.000111016
p_wrong: 0.003141128
Score: 0.188
Data Source: BioPlex,STRINGDB
CNTNAP3
Novelty: 0.22791524
p_int: 0.832248757
p_ni: 0.167751014
p_wrong: 2.28e-7
Score: 0.177
Data Source: BioPlex,STRINGDB
CDYL
Family: Epigenetic
Novelty: 0.03367841
p_int: 0.811884855
p_ni: 0.188114017
p_wrong: 0.000001128
Score: 0.205
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (9)
Reactome (9)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | G alpha (i) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of fat-soluble vitamins | ||||
Reactome | Metabolism of vitamins and cofactors | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
G alpha (i) signalling events | ||||
GPCR downstream signalling | ||||
Metabolism | ||||
Metabolism of fat-soluble vitamins | ||||
Metabolism of vitamins and cofactors | ||||
Viral Interactions (0)
Gene Ontology Terms (19)
Functions (3)
Components (6)
Processes (10)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Disease Associations ()
GWAS Traits (602)
Items per page:
1 – 5 of 602
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
1 | 3 | 0 | 3 | 96.3 | ||||||
1 | 3 | 0 | 3 | 96.3 | ||||||
1 | 3 | 0 | 3 | 96.3 | ||||||
1 | 3 | 0 | 3 | 96.3 | ||||||
1 | 3 | 0 | 3 | 96.3 | ||||||
Items per page:
1 – 5 of 602
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 3 | 96.3 | |||||
0 | 3 | 96.3 | |||||
0 | 3 | 96.3 | |||||
0 | 3 | 96.3 | |||||
0 | 3 | 96.3 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | apolipoprotein M | 715848 | ||||||
Mouse | MGI:1930124 | 55938 | ||||||
Rat | RGD:620773 | 55939 | ||||||
Dog | apolipoprotein M | VGNC:38008 | 474843 | |||||
Horse | apolipoprotein M | VGNC:15424 | 100050362 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | apolipoprotein M | |||||
Mouse | ||||||
Rat | ||||||
Dog | apolipoprotein M | |||||
Horse | apolipoprotein M | |||||
Publication Statistics
PubMed Score 261.91
PubMed score by year
PubTator Score 131.85
PubTator score by year
Related Publications
Text Mined References (113)
GeneRif Annotations (92)
Items per page:
0 of 0
PMID | Year | Title |
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