Tbio CNIH1 Protein cornichon homolog 1

Protein Summary

Description

Involved in the selective transport and maturation of TGF-alpha family proteins.

Uniprot Accession IDs

• O95406
• Q3SYM7
• CNIH-1

Gene Name

• CNIH1

Ensembl ID

• ENST00000216416
• ENSP00000216416
• ENSG00000100528

Symbol

• CNIH
• CNIL
• CNIH
• CNIL
• CNIH-1
• TGAM77

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.97
co-expressed gene	0.82
transcription factor binding site profile	0.81
histone modification site profile	0.7
tissue	0.67

Protein Classes

PANTHER Classes

Protein / Signaling Molecule / Membrane-bound Signaling Molecule / Protein Cornichon Homolog 1

Protein / Membrane Traffic Protein / Protein Cornichon Homolog 1

DTO Classes

Protein / Signaling / Membrane-bound Signaling Molecule / Protein Cornichon Homolog 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.4   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 81   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.4   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0