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Tbio
CNIH1
Protein cornichon homolog 1

Protein Summary
Description
Involved in the selective transport and maturation of TGF-alpha family proteins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000216416
  • ENSP00000216416
  • ENSG00000100528

Symbol
  • CNIH
  • CNIL
  • CNIH
  • CNIL
  • CNIH-1
  • TGAM77
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
co-expressed gene
0.82
transcription factor binding site profile
0.81
histone modification site profile
0.7
tissue
0.67


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.84   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.84   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cornichon family AMPA receptor auxiliary protein 1
VGNC:12775
452913
Mouse
MGI:1277202
12793
Horse
cornichon family AMPA receptor auxiliary protein 1 [Source:HGNC Symbol;Acc:HGNC:19431]
Cow
cornichon family AMPA receptor auxiliary protein 1
VGNC:27502
613575
Pig
cornichon family AMPA receptor auxiliary protein 1
100154949
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cornichon family AMPA receptor auxiliary protein 1
Mouse
Horse
cornichon family AMPA receptor auxiliary protein 1 [Source:HGNC Symbol;Acc:HGNC:19431]
Cow
cornichon family AMPA receptor auxiliary protein 1
Pig
cornichon family AMPA receptor auxiliary protein 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O95406-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (9)
Asparagine N-linked glycosylation (R-HSA-446203)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 9
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Asparagine N-linked glycosylation
Reactome
COPII-mediated vesicle transport
Reactome
Cargo concentration in the ER
Reactome
ER to Golgi Anterograde Transport
Reactome
Membrane Trafficking
Name
Explore in Pharos
Explore in Source
Asparagine N-linked glycosylation
COPII-mediated vesicle transport
Cargo concentration in the ER
ER to Golgi Anterograde Transport
Membrane Trafficking
Gene Ontology Terms (9)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Traceable Author Statement (TAS)
Reactome
Traceable Author Statement (TAS)
Reactome
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (118)
1 – 10 of 118
TMED10
Tbio
Novelty: 0.02742083
Score: 0.956
Data Source: STRINGDB
GRIA1
Tclin
Family: IC
Novelty: 0.0005008
Score: 0.955
Data Source: STRINGDB
SEC23A
Tbio
Novelty: 0.0384262
Score: 0.949
Data Source: STRINGDB
SEC24B
Tbio
Novelty: 0.01031644
Score: 0.949
Data Source: STRINGDB
SEC24D
Tbio
Novelty: 0.04795527
Score: 0.945
Data Source: STRINGDB
SEC24C
Tbio
Novelty: 0.05842956
Score: 0.941
Data Source: STRINGDB
SAR1B
Tbio
Family: Enzyme
Novelty: 0.02260817
Score: 0.938
Data Source: STRINGDB
SEC13
Tbio
Novelty: 0.00709413
Score: 0.934
Data Source: STRINGDB
TMED2
Tbio
Novelty: 0.03731104
Score: 0.932
Data Source: STRINGDB
SEC24A
Tbio
Novelty: 0.07724534
Score: 0.931
Data Source: STRINGDB
Publication Statistics
PubMed Score  10.84

PubMed score by year
PubTator Score  2.67

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer