You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
LUC7L3
Luc7-like protein 3

Protein Summary
Description
Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000240304
  • ENSP00000240304
  • ENSG00000108848
  • ENST00000505658
  • ENSP00000425092

Symbol
  • CREAP1
  • CROP
  • O48
  • CRA
  • CROP
  • LUC7A
  • hLuc7A
  • CREAP-1
  • OA48-18
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.94
transcription factor perturbation
0.91
disease perturbation
0.9
interacting protein
0.85
microRNA
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.93   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.93   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0