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Tbio
STBD1
Starch-binding domain-containing protein 1

Protein Summary
Description
Acts as a cargo receptor for glycogen. Delivers its cargo to an autophagic pathway called glycophagy, resulting in the transport of glycogen to lysosomes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000237642
  • ENSP00000237642
  • ENSG00000118804

Symbol
  • GENEX3414
  • GENX-3414
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.85
disease perturbation
0.74
small molecule perturbation
0.73
histone modification site profile
0.68
gene perturbation
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.36   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 94   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.36   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 94   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (115)
PRKAB2
Tchem
Family:  Enzyme
Novelty:  0.02815065
p_int:  0.999999883
p_ni:  1.17e-7
Score:  0.735
Data Source:  BioPlex,STRINGDB
O95278
Tbio
Family:  Enzyme
Novelty:  0.00846992
p_int:  0.999999857
p_ni:  1.2e-8
p_wrong:  1.31e-7
Score:  0.917
Data Source:  BioPlex,STRINGDB
GABARAPL1
Tbio
Novelty:  0.00212657
p_int:  0.999999775
p_ni:  1.5e-8
p_wrong:  2.1e-7
Score:  0.839
Data Source:  BioPlex,STRINGDB
PPP1R3C
Tbio
Family:  Enzyme
Novelty:  0.01784199
p_int:  0.999999413
p_ni:  4.6e-8
p_wrong:  5.41e-7
Score:  0.885
Data Source:  BioPlex,STRINGDB
GYG2
Tbio
Family:  Enzyme
Novelty:  0.01520991
p_int:  0.999999332
p_ni:  6.29e-7
p_wrong:  3.9e-8
Score:  0.605
Data Source:  BioPlex,STRINGDB
MID1
Tbio
Family:  Enzyme
Novelty:  0.02400169
p_int:  0.999999219
p_ni:  7.81e-7
Score:  0.228
Data Source:  BioPlex,STRINGDB
GBE1
Tbio
Family:  Enzyme
Novelty:  0.00233237
p_int:  0.999988558
p_ni:  0.000011442
Score:  0.9
Data Source:  BioPlex,STRINGDB
GABARAP
Tbio
Novelty:  0.00444901
p_int:  0.99998516
p_ni:  0.000014838
p_wrong:  2e-9
Score:  0.557
Data Source:  BioPlex,STRINGDB
GYS1
Tchem
Family:  Enzyme
Novelty:  0.00721964
p_int:  0.999972166
p_ni:  0.000027834
Score:  0.849
Data Source:  BioPlex,STRINGDB
KLRG2
Tdark
Novelty:  1.19446694
p_int:  0.999792467
p_ni:  0.000083977
p_wrong:  0.000123555
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (15)
Immune System (R-HSA-168256)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Immune System
Reactome
Innate Immune System
Reactome
Neutrophil degranulation
Name
Explore in Pharos
Explore in Source
Immune System
Innate Immune System
Neutrophil degranulation
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
6
2
6
93
creatinine measurement
1
4
4
86
glomerular filtration rate
1
4
4
85.6
alkaline phosphatase measurement
2
2
1
7
77.1
5
2
1
1.1
74
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
6
93
creatinine measurement
4
86
glomerular filtration rate
4
85.6
alkaline phosphatase measurement
1
7
77.1
1
1.1
74
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
starch binding domain 1
VGNC:12836
738648
Mouse
MGI:1261768
52331
Rat
RGD:1311800
305234
Dog
starch binding domain 1 [Source:HGNC Symbol;Acc:HGNC:24854]
Horse
starch binding domain 1
VGNC:23671
100058284
Species
Name
OMA
EggNOG
Inparanoid
Chimp
starch binding domain 1
Mouse
Rat
Dog
starch binding domain 1 [Source:HGNC Symbol;Acc:HGNC:24854]
Horse
starch binding domain 1
Publication Statistics
PubMed Score 15.36
PubMed score by year
PubTator Score 4.48
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title