NDUFA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.98 | ||
disease perturbation | 0.9 | ||
histone modification site profile | 0.84 | ||
kinase perturbation | 0.84 | ||
transcription factor binding site profile | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Complex I biogenesis | ||||
Reactome | Metabolism | ||||
Reactome | Respiratory electron transport | ||||
Reactome | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
Reactome | The citric acid (TCA) cycle and respiratory electron transport | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Complex I biogenesis | ||||
Metabolism | ||||
Respiratory electron transport | ||||
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
The citric acid (TCA) cycle and respiratory electron transport | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 13 | 8 | 20 | 4 | 99.5 | ||||
triglyceride measurement | 9 | 3 | 12 | 98 | |||||
apolipoprotein A 1 measurement | 2 | 3 | 4 | 97.1 | |||||
very long-chain saturated fatty acid measurement | 3 | 2 | 0 | 10 | 91.9 | ||||
red blood cell distribution width | 2 | 2 | 3 | 90.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 20 | 4 | 99.5 | ||||
triglyceride measurement | 12 | 98 | |||||
apolipoprotein A 1 measurement | 4 | 97.1 | |||||
very long-chain saturated fatty acid measurement | 0 | 10 | 91.9 | ||||
red blood cell distribution width | 3 | 90.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | NADH:ubiquinone oxidoreductase subunit A7 | 743262 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | NADH:ubiquinone oxidoreductase subunit A7 | |||||
PMID | Year | Title |
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