TNFSF15
Tumor necrosis factor ligand superfamily member 15
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.88 | ||
phenotype | 0.85 | ||
biological process | 0.75 | ||
trait | 0.75 | ||
biological term | 0.72 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Immune System | ||||
Reactome | TNFR2 non-canonical NF-kB pathway | ||||
Reactome | TNFs bind their physiological receptors | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytokine Signaling in Immune system | ||||
Immune System | ||||
TNFR2 non-canonical NF-kB pathway | ||||
TNFs bind their physiological receptors | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
8 | 8 | 0 | 1.4 | 97.6 | |||||
3 | 4 | 0 | 1.1 | 93.5 | |||||
2 | 2 | 0 | 1.4 | 92.1 | |||||
primary biliary cirrhosis | 3 | 2 | 0 | 1.6 | 90 | ||||
3 | 2 | 0 | 1.1 | 65.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.4 | 97.6 | |||||
0 | 1.1 | 93.5 | |||||
0 | 1.4 | 92.1 | |||||
primary biliary cirrhosis | 0 | 1.6 | 90 | ||||
0 | 1.1 | 65.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | TNF superfamily member 15 | VGNC:13980 | 473468 | |||||
Macaque | TNF superfamily member 15 | 703189 | ||||||
Mouse | MGI:2180140 | 326623 | ||||||
Rat | RGD:628735 | 252878 | ||||||
Dog | TNF superfamily member 15 | VGNC:47671 | 481688 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | TNF superfamily member 15 | |||||
Macaque | TNF superfamily member 15 | |||||
Mouse | ||||||
Rat | ||||||
Dog | TNF superfamily member 15 | |||||
PMID | Year | Title |
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