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Tdark
YIF1A
Protein YIF1A

Protein Summary
Description
Possible role in transport between endoplasmic reticulum and Golgi.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000376901
  • ENSP00000366098
  • ENSG00000174851

Symbol
  • 54TM
  • HYIF1P
  • YIF1
  • 54TM
  • YIF1
  • YIF1P
  • FinGER7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.9
transcription factor binding site profile
0.89
transcription factor
0.76
cellular component
0.75
histone modification site profile
0.74


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.02   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 35   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.02   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
Yip1 interacting factor homolog A, membrane trafficking protein
VGNC:6691
746258
Macaque
Yip1 interacting factor homolog A, membrane trafficking protein
714486
Mouse
MGI:1915340
68090
Rat
RGD:628749
171441
Dog
Yip1 interacting factor homolog A, membrane trafficking protein
VGNC:48485
476014
Species
Name
OMA
EggNOG
Inparanoid
Chimp
Yip1 interacting factor homolog A, membrane trafficking protein
Macaque
Yip1 interacting factor homolog A, membrane trafficking protein
Mouse
Rat
Dog
Yip1 interacting factor homolog A, membrane trafficking protein
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O95070-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
IRE1alpha activates chaperones (R-HSA-381070)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
IRE1alpha activates chaperones
Reactome
Metabolism of proteins
Reactome
Unfolded Protein Response (UPR)
Reactome
XBP1(S) activates chaperone genes
Name
Explore in Pharos
Explore in Source
IRE1alpha activates chaperones
Metabolism of proteins
Unfolded Protein Response (UPR)
XBP1(S) activates chaperone genes
Gene Ontology Terms (7)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (64)
1 – 10 of 64
ZNRF4
Tbio
Novelty: 0.16505328
p_int: 0.913500015
p_ni: 0.08649982
p_wrong: 1.65e-7
Data Source: BioPlex
SLAMF7
Tclin
Novelty: 0.01014396
p_int: 0.847893029
p_ni: 0.152106971
Score: 0.209
Data Source: BioPlex,STRINGDB
PCDHGB4
Tdark
Novelty: 0.25018904
p_int: 0.778664799
p_ni: 0.221334202
p_wrong: 9.99e-7
Data Source: BioPlex
TMEM9B
Tdark
Novelty: 0.56628366
p_int: 0.778187077
p_ni: 0.221811152
p_wrong: 0.00000177
Score: 0.189
Data Source: BioPlex,STRINGDB
YIPF5
Tbio
Novelty: 0.08206828
Score: 0.983
Data Source: STRINGDB
YIPF6
Tdark
Novelty: 0.04316252
Score: 0.849
Data Source: STRINGDB
VAPB
Tbio
Novelty: 0.00542377
Score: 0.746
Data Source: STRINGDB
COPE
Tbio
Novelty: 0.02037359
Score: 0.744
Data Source: STRINGDB
RABAC1
Tbio
Novelty: 0.01749453
Score: 0.733
Data Source: STRINGDB
YIPF4
Tdark
Novelty: 0.17862058
Score: 0.732
Data Source: STRINGDB
Publication Statistics
PubMed Score  14.02

PubMed score by year
PubTator Score  2.98

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer