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Tbio
FAM13A
Protein FAM13A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000264344
  • ENSP00000264344
  • ENSG00000138640
  • ENST00000395002
  • ENSP00000378450
  • ENST00000503556
  • ENSP00000427189
  • ENST00000508369
  • ENSP00000421562
  • ENST00000513837
  • ENSP00000423252

Symbol
  • FAM13A1
  • KIAA0914
  • FAM13A1
  • ARHGAP48
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
1
phenotype
0.85
transcription factor
0.74
kinase perturbation
0.66
microRNA
0.64


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.95   (req: < 5)
Gene RIFs: 21   (req: <= 3)
Antibodies: 35   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.95   (req: >= 5)
Gene RIFs: 21   (req: > 3)
Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (84)
UNC119
Tchem
Novelty:  0.00396292
p_int:  0.999999992
p_ni:  8e-9
Score:  0.232
Data Source:  BioPlex,STRINGDB
AHCYL1
Tchem
Family:  Enzyme
Novelty:  0.02176432
p_int:  0.999990145
p_ni:  0.000006754
p_wrong:  0.000003101
Data Source:  BioPlex
TBCCD1
Tbio
Novelty:  0.21991508
p_int:  0.999893475
p_ni:  0.0000158
p_wrong:  0.000090725
Score:  0.297
Data Source:  BioPlex,STRINGDB
RHOA
Tbio
Family:  Enzyme
Novelty:  0.00022204
Score:  0.925
Data Source:  STRINGDB
RAC2
Tbio
Family:  Enzyme
Novelty:  0.00116234
Score:  0.916
Data Source:  STRINGDB
RHOJ
Tbio
Family:  Enzyme
Novelty:  0.01217051
Score:  0.915
Data Source:  STRINGDB
RHOU
Tbio
Family:  Enzyme
Novelty:  0.01456329
Score:  0.915
Data Source:  STRINGDB
RHOBTB1
Tbio
Novelty:  0.02152609
Score:  0.915
Data Source:  STRINGDB
RHOQ
Tbio
Family:  Enzyme
Novelty:  0.00562425
Score:  0.914
Data Source:  STRINGDB
RHOBTB2
Tbio
Novelty:  0.00734789
Score:  0.914
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (16)
Rho GTPase cycle (R-HSA-194840)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Rho GTPase cycle
Reactome
Signal Transduction
Reactome
Signaling by Rho GTPases
Name
Explore in Pharos
Explore in Source
Rho GTPase cycle
Signal Transduction
Signaling by Rho GTPases
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (29)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
10
28
42
98.8
waist-hip ratio
3
26
27
98.7
waist circumference
1
12
12
94.9
FEV/FEC ratio
1
2
2
94.5
BMI-adjusted waist circumference
1
13
13
94.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
42
98.8
waist-hip ratio
27
98.7
waist circumference
12
94.9
FEV/FEC ratio
2
94.5
BMI-adjusted waist circumference
13
94.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 13 member A
VGNC:2995
742343
Macaque
family with sequence similarity 13 member A
703335
Mouse
MGI:1889842
58909
Rat
RGD:1309807
362378
Dog
family with sequence similarity 13 member A
VGNC:40596
487854
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 13 member A
Macaque
family with sequence similarity 13 member A
Mouse
Rat
Dog
family with sequence similarity 13 member A
Publication Statistics
PubMed Score 46.95
PubMed score by year
PubTator Score 24.14
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title