Tbio TMEM63A CSC1-like protein 1

Protein Summary

Description

Acts as an osmosensitive calcium-permeable cation channel.

Uniprot Accession IDs

• O94886
• Q53GI7
• Q5TE96
• Q8N2U2

Gene Name

• TMEM63A

Ensembl ID

• ENST00000366835
• ENSP00000355800
• ENSG00000196187

Symbol

• KIAA0489
• KIAA0792
• KIAA0792

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.85
transcription factor	0.72
transcription factor perturbation	0.68
kinase perturbation	0.66
cellular component	0.65

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.13   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 72   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.13   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0