Tbio SUPT7L STAGA complex 65 subunit gamma

Protein Summary

Description

SUPT7L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]

Uniprot Accession IDs

• O94864
• B4E3W3
• Q6IB21
• Q9H2T6

Gene Name

• SUPT7L

Ensembl ID

• ENST00000337768
• ENSP00000336750
• ENSG00000119760
• ENST00000404798
• ENSP00000385218
• ENST00000405491
• ENSP00000384469
• ENST00000406540
• ENSP00000385436
• ENST00000464789
• ENSP00000441110

Symbol

• KIAA0764
• SPT7L
• STAF65
• SUPT7H
• STAF65G
• STAF65(gamma)

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.93
virus perturbation	0.92
transcription factor binding site profile	0.71
microRNA	0.65
biological process	0.62

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.73   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 90   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.73   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 90   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0