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Tbio
TOMM70
Mitochondrial import receptor subunit TOM70

Protein Summary
Description
Receptor that accelerates the import of all mitochondrial precursor proteins. This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. This protein is involved in the import of mitochondrial precursor proteins. [provided by RefSeq, Oct 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000284320
  • ENSP00000284320
  • ENSG00000154174

Symbol
  • KIAA0719
  • TOM70
  • TOMM70A
  • Tom70
  • TOMM70A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 109.23   (req: < 5)
Gene RIFs: 17   (req: <= 3)
Antibodies: 211   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 109.23   (req: >= 5)
Gene RIFs: 17   (req: > 3)
Antibodies: 211   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (136)
TOMM22
Tbio
Novelty:  0.01217913
Score:  0.999
Data Source:  STRINGDB
TOMM40
Tbio
Novelty:  0.0041507
Score:  0.998
Data Source:  STRINGDB
TOMM7
Tbio
Novelty:  0.03885154
Score:  0.998
Data Source:  STRINGDB
TOMM20
Tbio
Novelty:  0.00275824
Score:  0.996
Data Source:  STRINGDB
TOMM5
Tdark
Novelty:  0.07962801
Score:  0.98
Data Source:  STRINGDB
TOMM6
Tbio
Novelty:  0.1033676
Score:  0.979
Data Source:  STRINGDB
TIMM50
Tbio
Family:  Enzyme
Novelty:  0.0238053
Score:  0.979
Data Source:  STRINGDB
TIMM22
Tbio
Family:  Enzyme
Novelty:  0.12627933
Score:  0.978
Data Source:  STRINGDB
VDAC1
Tbio
Novelty:  0.0011441
Score:  0.978
Data Source:  STRINGDB
HSPA9
Tchem
Novelty:  0.00235171
Score:  0.966
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (11)
Autophagy (R-HSA-9612973)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 11
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Autophagy
Reactome
Cellular responses to external stimuli
Reactome
Deubiquitination
Reactome
Macroautophagy
Reactome
Metabolism of proteins
Name
Explore in Pharos
Explore in Source
Autophagy
Cellular responses to external stimuli
Deubiquitination
Macroautophagy
Metabolism of proteins
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
refractive error measurement
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
refractive error measurement
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
translocase of outer mitochondrial membrane 70
VGNC:8847
470872
Macaque
translocase of outer mitochondrial membrane 70
700347
Mouse
MGI:106295
28185
Dog
translocase of outer mitochondrial membrane 70
VGNC:49630
478541
Horse
translocase of outer mitochondrial membrane 70
VGNC:49123
100072274
Species
Name
OMA
EggNOG
Inparanoid
Chimp
translocase of outer mitochondrial membrane 70
Macaque
translocase of outer mitochondrial membrane 70
Mouse
Dog
translocase of outer mitochondrial membrane 70
Horse
translocase of outer mitochondrial membrane 70
Publication Statistics
PubMed Score 109.23
PubMed score by year
PubTator Score 37.92
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title