SLIT2
Slit homolog 2 protein
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
protein domain | 1 | ||
PubMedID | 0.98 | ||
molecular function | 0.91 | ||
histone modification site profile | 0.78 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of RAC1 | ||||
Reactome | Axon guidance | ||||
Reactome | Developmental Biology | ||||
Reactome | Inactivation of CDC42 and RAC1 | ||||
Reactome | Netrin-1 signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of RAC1 | ||||
Axon guidance | ||||
Developmental Biology | ||||
Inactivation of CDC42 and RAC1 | ||||
Netrin-1 signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body mass index | 2 | 2 | 2 | 61.9 | |||||
smoking status measurement | 1 | 1 | 1 | 35 | |||||
2 | 2 | 2 | 26.1 | ||||||
serum metabolite measurement | 1 | 1 | 1 | 4.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body mass index | 2 | 61.9 | |||||
smoking status measurement | 1 | 35 | |||||
2 | 26.1 | ||||||
serum metabolite measurement | 1 | 4.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | slit guidance ligand 2 | VGNC:738 | 461137 | |||||
Macaque | slit guidance ligand 2 | 715470 | ||||||
Mouse | MGI:1315205 | 20563 | ||||||
Dog | slit guidance ligand 2 | VGNC:46504 | 595148 | |||||
Horse | slit guidance ligand 2 | VGNC:51322 | 100068338 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | slit guidance ligand 2 | |||||
Macaque | slit guidance ligand 2 | |||||
Mouse | ||||||
Dog | slit guidance ligand 2 | |||||
Horse | slit guidance ligand 2 | |||||
PMID | Year | Title |
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