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Tchem
STK17B
Serine/threonine-protein kinase 17B

Protein Summary
Description
Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263955
  • ENSP00000263955
  • ENSG00000081320
  • ENST00000409228
  • ENSP00000386853

Symbol
  • DRAK2
  • DRAK2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.98
molecular function
0.9
transcription factor binding site profile
0.84
PubMedID
0.81
protein domain
0.73


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.22   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 403   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.22   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 403   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 24
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 1