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Tbio
SCGN
Secretagogin

Protein Summary
Description
The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000377961
  • ENSP00000367197
  • ENSG00000079689

Symbol
  • SECRET
  • SEGN
  • CALBL
  • SECRET
  • setagin
  • DJ501N12.8
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.68
trait
0.61
PubMedID
0.59
gene perturbation
0.58
tissue
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 90.1   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 306   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 90.1   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 306   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin D measurement
1
1
1
68.6
mathematical ability
1
1
1
58.9
wellbeing measurement
2
1
2
30.8
1
1
0
1.3
27.7
depressive symptom measurement
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin D measurement
1
68.6
mathematical ability
1
58.9
wellbeing measurement
2
30.8
0
1.3
27.7
depressive symptom measurement
1
24.5
Gene Ontology Terms (13)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (84)
1 – 10 of 84
AGGF1
Tbio
Novelty: 0.02757407
p_int: 0.999998938
p_ni: 0.000001062
Data Source: BioPlex
RAVER1
Tbio
Novelty: 0.08620158
p_int: 0.999994446
p_ni: 0.000005554
Score: 0.171
Data Source: BioPlex,STRINGDB
ATF7
Tbio
Family: TF
Novelty: 0.01470313
p_int: 0.99998801
p_ni: 0.00001199
Score: 0.289
Data Source: BioPlex,STRINGDB
KIF14
Tbio
Novelty: 0.02313641
p_int: 0.999979457
p_ni: 0.000020543
Score: 0.198
Data Source: BioPlex,STRINGDB
DOC2A
Tbio
Novelty: 0.07489914
p_int: 0.999935279
p_ni: 0.000064721
Score: 0.248
Data Source: BioPlex,STRINGDB
PHKG2
Tchem
Family: Kinase
Novelty: 0.064884
p_int: 0.999787334
p_ni: 0.000191702
p_wrong: 0.000020964
Score: 0.258
Data Source: BioPlex,STRINGDB
NBR1
Tbio
Novelty: 0.00893066
p_int: 0.999693375
p_ni: 0.000237374
p_wrong: 0.000069251
Score: 0.295
Data Source: BioPlex,STRINGDB
GOLGB1
Tbio
Novelty: 0.00943584
p_int: 0.999674669
p_ni: 0.000325331
Score: 0.19
Data Source: BioPlex,STRINGDB
ATF2
Tbio
Family: TF
Novelty: 0.00457832
p_int: 0.998657253
p_ni: 0.000456107
p_wrong: 0.00088664
Score: 0.196
Data Source: BioPlex,STRINGDB
OPA1
Tbio
Novelty: 0.0031868
p_int: 0.998570777
p_ni: 0.001429223
Score: 0.202
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  90.10

PubMed score by year
PubTator Score  44.55

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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