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Tbio
NCR1
Natural cytotoxicity triggering receptor 1

Protein Summary
Description
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000350790
  • ENSP00000344358
  • ENSG00000189430
  • ENST00000357397
  • ENSP00000349972
  • ENST00000610621
  • ENSP00000483452
  • ENSG00000273535
  • ENST00000610753
  • ENSP00000484377
  • ENST00000611098
  • ENSP00000479222
  • ENSG00000275156
  • ENST00000611105
  • ENSP00000483028
  • ENSG00000278362
  • ENST00000611942
  • ENSP00000483723
  • ENST00000612239
  • ENSP00000481692
  • ENST00000612645
  • ENSP00000481540
  • ENST00000612896
  • ENSP00000484520
  • ENST00000613135
  • ENSP00000480145
  • ENST00000613556
  • ENSP00000482092
  • ENST00000615622
  • ENSP00000478507
  • ENST00000617154
  • ENSP00000481971
  • ENST00000617784
  • ENSP00000482423
  • ENST00000618973
  • ENSP00000483611
  • ENST00000619077
  • ENSP00000484221
  • ENST00000619451
  • ENSP00000482536
  • ENST00000620296
  • ENSP00000484067
  • ENST00000621059
  • ENSP00000484831
  • ENST00000621652
  • ENSP00000477625
  • ENST00000639155
  • ENSP00000491020
  • ENSG00000284113
  • ENST00000640377
  • ENSP00000491933
  • ENSG00000284208
  • ENST00000640753
  • ENSP00000492673
  • ENST00000640987
  • ENSP00000492426

Symbol
  • LY94
  • LY94
  • CD335
  • NKP46
  • NK-p46
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.72
cellular component
0.69
biological term
0.64
tissue
0.61
phenotype
0.58


Protein Classes
PANTHER Classes Protein / Signaling Molecule / Membrane-bound Signaling Molecule / Natural Cytotoxicity Triggering Receptor 1 Protein / Receptor / Cytokine Receptor / Immunoglobulin Receptor Superfamily / Natural Cytotoxicity Triggering Receptor 1 Protein / Defense/immunity Protein / Immunoglobulin Receptor Superfamily / Natural Cytotoxicity Triggering Receptor 1 Protein / ... / Protease Inhibitor / Natural Cytotoxicity Triggering Receptor 1
DTO ClassesProtein / Receptor / Cytokine Receptor / Immunoglobulin Receptor Superfamily / Natural Cytotoxicity Triggering Receptor 1
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 428.92   (req: < 5)
View Publications
Gene RIFs: 75   (req: <= 3)
View Gene RIFs
Antibodies: 684   (req: <= 50)
View Antibodies
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 428.92   (req: >= 5)
Gene RIFs: 75   (req: > 3)
Antibodies: 684   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
View GO Terms
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0