You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
NCR1
Natural cytotoxicity triggering receptor 1

Protein Summary
Description
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000350790
  • ENSP00000344358
  • ENSG00000189430
  • ENST00000357397
  • ENSP00000349972
  • ENST00000610621
  • ENSP00000483452
  • ENSG00000273535
  • ENST00000610753
  • ENSP00000484377
  • ENST00000611098
  • ENSP00000479222
  • ENSG00000275156
  • ENST00000611105
  • ENSP00000483028
  • ENSG00000278362
  • ENST00000611942
  • ENSP00000483723
  • ENST00000612239
  • ENSP00000481692
  • ENST00000612645
  • ENSP00000481540
  • ENST00000612896
  • ENSP00000484520
  • ENST00000613135
  • ENSP00000480145
  • ENST00000613556
  • ENSP00000482092
  • ENST00000615622
  • ENSP00000478507
  • ENST00000617154
  • ENSP00000481971
  • ENST00000617784
  • ENSP00000482423
  • ENST00000618973
  • ENSP00000483611
  • ENST00000619077
  • ENSP00000484221
  • ENST00000619451
  • ENSP00000482536
  • ENST00000620296
  • ENSP00000484067
  • ENST00000621059
  • ENSP00000484831
  • ENST00000621652
  • ENSP00000477625
  • ENST00000639155
  • ENSP00000491020
  • ENSG00000284113
  • ENST00000640377
  • ENSP00000491933
  • ENSG00000284208
  • ENST00000640753
  • ENSP00000492673
  • ENST00000640987
  • ENSP00000492426

Symbol
  • LY94
  • LY94
  • CD335
  • NKP46
  • NK-p46
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.72
cellular component
0.69
biological term
0.64
tissue
0.61
phenotype
0.58


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 428.92   (req: < 5)
Gene RIFs: 73   (req: <= 3)
Antibodies: 684   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 428.92   (req: >= 5)
Gene RIFs: 73   (req: > 3)
Antibodies: 684   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0