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Tbio
RSL1D1
Ribosomal L1 domain-containing protein 1

Protein Summary
Description
Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000571133
  • ENSP00000460871
  • ENSG00000171490

Symbol
  • CATX11
  • CSIG
  • PBK1
  • L12
  • CSIG
  • PBK1
  • UTP30
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
1
drug perturbation
0.96
disease perturbation
0.95
virus perturbation
0.95
histone modification site profile
0.9


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.26   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 133   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.26   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 133   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0