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Tbio
OR2J3
Olfactory receptor 2J3

Protein Summary
Description
Odorant receptor involved in the detection of the flavor compound cis-3-hexen-1-ol (C3HEX), a compound typically described as 'green grassy' or the smell of 'cut grass'. This gene encodes a G-protein-coupled receptor (GPCR) that functions as an olfactory receptor. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The protein encoded by this gene responds to cis-3-hexen-1-ol, which is released by wounded plants, including cut grass. This gene is situated in a cluster of similar olfactory-receptor coding genes on chromosome 6. [provided by RefSeq, May 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000377169
  • ENSP00000366374
  • ENSG00000204701
  • ENST00000383651
  • ENSP00000373147
  • ENSG00000206522
  • ENST00000414140
  • ENSP00000390144
  • ENSG00000232178
  • ENST00000418630
  • ENSP00000400546
  • ENSG00000233618
  • ENST00000419260
  • ENSP00000408783
  • ENSG00000229866
  • ENST00000428081
  • ENSP00000388392
  • ENSG00000226271
  • ENST00000430478
  • ENSP00000388205
  • ENSG00000233636

Symbol
  • 6M1-3
  • OR6-6
  • C3HEXS
  • OR6-16
  • ORL671
  • HS6M1-3
  • OR6.3.6
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.85
cell line
0.5
tissue sample
0.46
protein domain
0.41
microRNA
0.35


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.7   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 83   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.7   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0