Protein Summary
Odorant receptor involved in the detection of the flavor compound cis-3-hexen-1-ol (C3HEX), a compound typically described as 'green grassy' or the smell of 'cut grass'. This gene encodes a G-protein-coupled receptor (GPCR) that functions as an olfactory receptor. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The protein encoded by this gene responds to cis-3-hexen-1-ol, which is released by wounded plants, including cut grass. This gene is situated in a cluster of similar olfactory-receptor coding genes on chromosome 6. [provided by RefSeq, May 2013]
- ENST00000377169
- ENSP00000366374
- ENSG00000204701
- ENST00000383651
- ENSP00000373147
- ENSG00000206522
- ENST00000414140
- ENSP00000390144
- ENSG00000232178
- ENST00000418630
- ENSP00000400546
- ENSG00000233618
- ENST00000419260
- ENSP00000408783
- ENSG00000229866
- ENST00000428081
- ENSP00000388392
- ENSG00000226271
- ENST00000430478
- ENSP00000388205
- ENSG00000233636
- 6M1-3
- OR6-6
- C3HEXS
- OR6-16
- ORL671
- HS6M1-3
- OR6.3.6
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.85 | ||
cell line | 0.5 | ||
tissue sample | 0.46 | ||
protein domain | 0.41 | ||
microRNA | 0.35 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.09 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 83 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.09 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 83 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Pathways (7)
Reactome (5)
KEGG (1)
WikiPathways (1)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 5 of 5
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | G alpha (s) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | Olfactory Signaling Pathway | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by GPCR | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
G alpha (s) signalling events | ||||
GPCR downstream signalling | ||||
Olfactory Signaling Pathway | ||||
Signal Transduction | ||||
Signaling by GPCR | ||||
Gene Ontology Terms (4)
Functions (2)
Components (2)
Items per page:
10
1 – 2 of 2
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Protein-Protein Interactions (29)
1 – 10 of 29
RTP2
Novelty: 0.13129103
Score: 0.94
Data Source: STRINGDB
RTP1
Novelty: 0.04761905
Score: 0.921
Data Source: STRINGDB
REEP1
Novelty: 0.02999447
Score: 0.921
Data Source: STRINGDB
GNAL
Novelty: 0.0277957
Score: 0.917
Data Source: STRINGDB
GNB1
Novelty: 0.04716243
Score: 0.9
Data Source: STRINGDB
REEP6
Novelty: 0.17493781
Score: 0.9
Data Source: STRINGDB
RTP3
Novelty: 0.12230635
Score: 0.9
Data Source: STRINGDB
REEP2
Novelty: 0.28121006
Score: 0.9
Data Source: STRINGDB
REEP4
Novelty: 0.34354551
Score: 0.9
Data Source: STRINGDB
RTP4
Novelty: 0.18444058
Score: 0.9
Data Source: STRINGDB
Publication Statistics
PubMed Score 3.09
PubMed score by year
PubTator Score 47.78
PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Sequence
MNDDGKVNASSEGYFILVGFSNWPHLEVVIFVVVLIFYLMTLIGNLFIIILSYLDSHLHTPMYFFLSNLS
1-70
FLDLCYTTSSIPQLLVNLWGPEKTISYAGCMIQLYFVLALGTTECVLLVVMSYDRYAAVCRPLHYTVLMH
70-140
PRFCHLLAVASWVSGFTNSALHSSFTFWVPLCGHRQVDHFFCEVPALLRLSCVDTHVNELTLMITSSIFV
140-210
LIPLILILTSYGAIVRAVLRMQSTTGLQKVFGTCGAHLMAVSLFFIPAMCIYLQPPSGNSQDQGKFIALF
210-280
YTVVTPSLNPLIYTLRNKVVRGAVKRLMGWE
280-311
MNDDGKVNASSEGYFILVGFSNWPHLEVVIFVVVLIFYLMTLIGNLFIIILSYLDSHLHTPMYFFLSNLSFLDLCYTTSSIPQLLVNLWGPEKTISYAGCMIQLYFVLALGTTECVLLVVMSYDRYAAVCRPLHYTVLMHPRFCHLLAVASWVSGFTNSALHSSFTFWVPLCGHRQVDHFFCEVPALLRLSCVDTHVNELTLMITSSIFVLIPLILILTSYGAIVRAVLRMQSTTGLQKVFGTCGAHLMAVSLFFIPAMCIYLQPPSGNSQDQGKFIALFYTVVTPSLNPLIYTLRNKVVRGAVKRLMGWE
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