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Tdark
C1QL1
C1q-related factor

Protein Summary
Description
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253407
  • ENSP00000253407
  • ENSG00000131094

Symbol
  • C1QRF
  • CRF
  • CTRP14
  • CRF
  • C1QRF
  • CTRP14
  • C1QTNF14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.74
cell type or tissue
0.68
PubMedID
0.65
tissue sample
0.64
histone modification site profile
0.56


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.56   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.56   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
25.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
25.3
Gene Ontology Terms (10)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (47)
1 – 10 of 47
LAIR2
Tbio
Novelty: 0.06117644
p_int: 0.999929051
p_ni: 0.000070946
p_wrong: 3e-9
Data Source: BioPlex
COL10A1
Tbio
Novelty: 0.00521991
p_int: 0.999474253
p_ni: 0.000520165
p_wrong: 0.000005583
Score: 0.18
Data Source: BioPlex,STRINGDB
CD1E
Tbio
Novelty: 0.00171622
p_int: 0.997490289
p_ni: 0.002509708
p_wrong: 3e-9
Data Source: BioPlex
TMEM30B
Tbio
Novelty: 0.26735006
p_int: 0.996747423
p_ni: 0.002706043
p_wrong: 0.000546534
Data Source: BioPlex
HTR3A
Tclin
Family: IC
Novelty: 0.00217443
p_int: 0.996606568
p_ni: 0.002911314
p_wrong: 0.000482118
Data Source: BioPlex
CBLN4
Tbio
Novelty: 0.11296355
p_int: 0.996449115
p_ni: 0.003092565
p_wrong: 0.000458321
Score: 0.203
Data Source: BioPlex,STRINGDB
IFNLR1
Tbio
Novelty: 0.01990628
p_int: 0.996111799
p_ni: 0.003882308
p_wrong: 0.000005893
Data Source: BioPlex
ADIPOQ
Tbio
Novelty: 0.00011196
p_int: 0.992985532
p_ni: 0.005846679
p_wrong: 0.001167789
Data Source: BioPlex
CD160
Tbio
Novelty: 0.01511748
p_int: 0.990103754
p_ni: 0.009892917
p_wrong: 0.000003329
Data Source: BioPlex
CHRNB4
Tclin
Family: IC
Novelty: 0.01151716
p_int: 0.987241141
p_ni: 0.010036009
p_wrong: 0.002722849
Data Source: BioPlex
Publication Statistics
PubMed Score  8.56

PubMed score by year
PubTator Score  361.3

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer