MMP23B
Matrix metalloproteinase-23
Protein Summary
Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity). This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008]
- ENST00000356026
- ENSP00000348308
- ENSG00000189409
- MMP21
- MMP22
- MIFR
- MMP22
- MIFR-1
- MMP23A
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.99 | ||
transcription factor | 0.57 | ||
disease | 0.54 | ||
tissue sample | 0.54 | ||
PubMedID | 0.51 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 43.49 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 327 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 43.49 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 327 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0