ALDH1L1
Cytosolic 10-formyltetrahydrofolate dehydrogenase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
transcription factor perturbation | 0.88 | ||
kinase perturbation | 0.76 | ||
trait | 0.75 | ||
transcription factor | 0.67 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of folate and pterines | ||||
Reactome | Metabolism of vitamins and cofactors | ||||
Reactome | Metabolism of water-soluble vitamins and cofactors | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of folate and pterines | ||||
Metabolism of vitamins and cofactors | ||||
Metabolism of water-soluble vitamins and cofactors | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glycine measurement | 4 | 2 | 4 | 90.3 | |||||
urate measurement | 3 | 3 | 3 | 70.5 | |||||
glomerular filtration rate | 1 | 1 | 1 | 61.4 | |||||
serum metabolite measurement | 2 | 1 | 2 | 59.6 | |||||
homocysteine measurement | 1 | 1 | 1 | 56.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glycine measurement | 4 | 90.3 | |||||
urate measurement | 3 | 70.5 | |||||
glomerular filtration rate | 1 | 61.4 | |||||
serum metabolite measurement | 2 | 59.6 | |||||
homocysteine measurement | 1 | 56.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | aldehyde dehydrogenase 1 family member L1 | 716977 | ||||||
Mouse | MGI:1340024 | 107747 | ||||||
Rat | RGD:621294 | 64392 | ||||||
Horse | aldehyde dehydrogenase 1 family member L1 | VGNC:15232 | 100061108 | |||||
Cow | aldehyde dehydrogenase 1 family member L1 | VGNC:25811 | 505677 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | aldehyde dehydrogenase 1 family member L1 | |||||
Mouse | ||||||
Rat | ||||||
Horse | aldehyde dehydrogenase 1 family member L1 | |||||
Cow | aldehyde dehydrogenase 1 family member L1 | |||||
PMID | Year | Title |
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