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Tbio
GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

Protein Classes
Protein Summary
Description
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263985
  • ENSP00000263985
  • ENSG00000059691

Symbol
  • PET112
  • PET112L
  • PET112
  • HSPC199
  • PET112L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.94
histone modification site profile
0.92
molecular function
0.91
protein domain
0.85
transcription factor
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.32   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 127   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.32   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 127   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein-Protein Interactions (99)
1 – 10 of 99
GATC
Tbio
Family: Enzyme
p_int: 0.99999998
p_ni: 2e-8
Score: 0.982
Data Source: BioPlex,STRINGDB
QRSL1
Tbio
Family: Enzyme
Novelty: 0.01168333
p_int: 0.999999329
p_ni: 6.71e-7
Score: 0.999
Data Source: BioPlex,STRINGDB
GLB1L3
Tdark
Family: Enzyme
Novelty: 1.68674699
p_int: 0.982146456
p_ni: 0.017847955
p_wrong: 0.000005589
Data Source: BioPlex
CD1A
Tbio
Novelty: 0.00133941
p_int: 0.975842486
p_ni: 0.024157505
p_wrong: 9e-9
Data Source: BioPlex
LRP1
Tbio
Novelty: 0.00117899
p_int: 0.969059314
p_ni: 0.030940686
Score: 0.155
Data Source: BioPlex,STRINGDB
TNFSF8
Tbio
Novelty: 0.01609818
p_int: 0.938850082
p_ni: 0.061149914
p_wrong: 4e-9
Data Source: BioPlex
LINC01561
Tdark
p_int: 0.92914848
p_ni: 0.070851497
p_wrong: 2.4e-8
Data Source: BioPlex
ADAM18
Tdark
Family: Enzyme
Novelty: 0.24489796
p_int: 0.925640603
p_ni: 0.074358651
p_wrong: 7.46e-7
Data Source: BioPlex
MRPL12
Tbio
Novelty: 0.16043959
p_int: 0.90017908
p_ni: 0.099820912
p_wrong: 8e-9
Data Source: BioPlex
MGARP
Tbio
Novelty: 0.03593252
p_int: 0.896948074
p_ni: 0.103050358
p_wrong: 0.000001567
Data Source: BioPlex
Publication Statistics
PubMed Score  38.32

PubMed score by year
PubTator Score  5.45

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer