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Tbio
TRAPPC6A
Trafficking protein particle complex subunit 6A

Protein Summary
Description
May play a role in vesicular transport during the biogenesis of melanosomes. This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein may be involved in melanosome biogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000006275
  • ENSP00000006275
  • ENSG00000007255
  • ENST00000585934
  • ENSP00000468612
  • ENST00000588062
  • ENSP00000468363
  • ENST00000592647
  • ENSP00000468182

Symbol
  • TRS33
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.72
transcription factor perturbation
0.68
transcription factor
0.66
gene perturbation
0.57
tissue sample
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.75   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 118   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.75   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0