Tbio UTP20 Small subunit processome component 20 homolog

Protein Summary

Description

Involved in 18S pre-rRNA processing. Associates with U3 snoRNA. UTP20 is a component of the U3 small nucleolar RNA (snoRNA) (SNORD3A; MIM 180710) protein complex (U3 snoRNP) and is involved in 18S rRNA processing (Wang et al., 2007 [PubMed 17498821]).[supplied by OMIM, Jun 2009]

Uniprot Accession IDs

• O75691
• Q9H3H4

Gene Name

• UTP20

Ensembl ID

• ENST00000261637
• ENSP00000261637
• ENSG00000120800

Symbol

• DRIM
• DRIM
• 1A6/DRIM

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.98
virus perturbation	0.9
histone modification site profile	0.89
kinase perturbation	0.81
hub protein	0.75

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.68   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 41   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.68   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 41   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0